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Isoprenaline
🥰Excellent
Catalog No. T21411Cas No. 7683-59-2
Alias Novodrin, Norisodrine, Medihaler-Iso, Isuprel, Isoprenaline
Isoprenaline(Norisodrine) is a non-selective and orally active β-adrenoceptor agonist.Isoproterenol is a potent peripheral vasodilator and bronchodilator.Isoproterenol can be used in the study of bradycardia and bronchial asthma for the treatment of heart block, bradycardia.
Isoprenaline
🥰Excellent
Purity: 99.31%
Catalog No. T21411Alias Novodrin, Norisodrine, Medihaler-Iso, Isuprel, IsoprenalineCas No. 7683-59-2
Isoprenaline(Norisodrine) is a non-selective and orally active β-adrenoceptor agonist.Isoproterenol is a potent peripheral vasodilator and bronchodilator.Isoproterenol can be used in the study of bradycardia and bronchial asthma for the treatment of heart block, bradycardia.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 10 mg | $54 | In Stock | |
| 25 mg | $104 | In Stock | |
| 50 mg | $175 | In Stock | |
| 100 mg | $283 | In Stock |
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Purity:99.31%
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Product Introduction
Bioactivity
Chemical Properties
| Description | Isoprenaline(Norisodrine) is a non-selective and orally active β-adrenoceptor agonist.Isoproterenol is a potent peripheral vasodilator and bronchodilator.Isoproterenol can be used in the study of bradycardia and bronchial asthma for the treatment of heart block, bradycardia. |
| In vitro | Isoproterenol (300 nM, 3 minutes) increased the activity of low-Km cAMP Phosphodiesterase (cAMP PDE) inhibited by granule cGMP and cilotamide by about 100% in intact rat adipocytes.[1]
Isoprenaline (20 nM) increases the amplitude of total iK and causes a negative shift of approximately 10 mV in the activation curve for iK, both in the absence and in the presence of 300 nM nisoldipine to block the L-type Ca2+ current. Isoprenaline increases the spontaneous pacemaker rate of sino-atrial node pacemaker cells by 16% in rabbit-isolated pacemaker cells.[5] |
| In vivo | Isoproterenol (0.27-0. 64 μg/kg; oral; dog) is widely metabolized in dogs through relatively small amounts of reactions.[6] |
| Synonyms | Novodrin, Norisodrine, Medihaler-Iso, Isuprel, Isoprenaline |
| Molecular Weight | 211.26 |
| Formula | C11H17NO3 |
| Cas No. | 7683-59-2 |
| Smiles | C(CNC(C)C)(O)C1=CC(O)=C(O)C=C1 |
| Relative Density. | 1.1240 g/cm3 (Estimated) |
Storage & Solubility Information
| Storage | store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
| Solubility Information | DMSO: Soluble H2O: Insoluble |
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In Vivo Formulation Calculator (Clear solution)
Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . A total of 10 animals were administered, and the formula you used is 5% 
DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
Dose Conversion
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Tech Support
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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