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RIP2 kinase inhibitor 2

Name: RIP2 kinase inhibitor 2
Brand: TargetMol
SKU: T16753
Rating: 4.5 (1 reviews)

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Catalog No. T16753Cas No. 1581270-11-2

RIP2 kinase inhibitor 2 is a compound that inhibits receptor-interacting protein-2 kinase (RIP2).

RIP2 kinase inhibitor 2

😃Good

Catalog No. T16753Cas No. 1581270-11-2

RIP2 kinase inhibitor 2 is a compound that inhibits receptor-interacting protein-2 kinase (RIP2).

Pack Size	Price	Availability
2 mg	$196	5 days
5 mg	$347	5 days
25 mg	$1,140	8-10 weeks
50 mg	$1,490	8-10 weeks
100 mg	$1,990	8-10 weeks
1 mL x 10 mM (in DMSO)	$328	5 days

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Product Introduction

Bioactivity

Description	RIP2 kinase inhibitor 2 is a compound that inhibits receptor-interacting protein-2 kinase (RIP2).
In vitro	RIP2 kinase inhibitor 2 is a novel prodrug of a quinazoline amine that inhibits RIP2 kinase, which associates with NODI or NOD2 and functions primarily as a molecular scaffold to assemble other kinases involved in NF-κΒ and mitogen-activated protein kinase activation [1].

Chemical Properties

Molecular Weight	432.54
Formula	C₂₁H₂₈N₄O₄S
Cas No.	1581270-11-2
Relative Density.	1.266 g/cm3 (Predicted)

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 5 mg/mL (11.56 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	2.3119 mL	11.5596 mL	23.1192 mL	115.5962 mL
5 mM	0.4624 mL	2.3119 mL	4.6238 mL	23.1192 mL
10 mM	0.2312 mL	1.1560 mL	2.3119 mL	11.5596 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc