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SEMA4C Protein, Mouse, Recombinant (hFc)
(Synonyms: Semaphorin-C-like 1, Semaphorin-4C, Semaphorin I, Semai, Semacl1, Sema4c, Sema I, S4c, M-Sema F) Copy Product InfoSynonyms: Semaphorin-C-like 1, Semaphorin-4C, Semaphorin I, Semai, Semacl1, Sema4c, Sema I, S4c, M-Sema F
Catalog No. TMPJ-01176 Copy Product Info
Semaphorin-4C is a protein which belongs to the semaphorin family, contains 1 Ig-like C2-type domain, 1 PSI domain, 1 Sema domain. As cell surface receptor for PLXNB2, it plays an important role in cell-cell signaling. PLXNB2 binding promotes downstream activation of RHOA and phosphorylation of ERBB2 at 'Tyr-1248'. It required for normal brain development, axon guidance and cell migration, Probable signaling receptor which may play a role in myogenic differentiation through activation of the stress-activated MAPK cascade.
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| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 5 μg | $112 | 6-8 weeks | 6-8 weeks | |
| 10 μg | $183 | 6-8 weeks | 6-8 weeks | |
| 20 μg | $292 | 6-8 weeks | 6-8 weeks | |
| 50 μg | $545 | 6-8 weeks | 6-8 weeks | |
| 100 μg | $792 | 6-8 weeks | 6-8 weeks | |
| 200 μg | $1,150 | 6-8 weeks | 6-8 weeks | |
| 500 μg | $1,900 | 6-8 weeks | 6-8 weeks | |
| 1 mg | $2,970 | 6-8 weeks | 6-8 weeks |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction
Bioactivity
Chemical Properties
Storage & Solubility Information
| Bioactivity | Activity has not been tested. It is theoretically active, but we cannot guarantee it. If you require protein activity, we recommend choosing the eukaryotic expression version first. |
| Description | Semaphorin-4C is a protein which belongs to the semaphorin family, contains 1 Ig-like C2-type domain, 1 PSI domain, 1 Sema domain. As cell surface receptor for PLXNB2, it plays an important role in cell-cell signaling. PLXNB2 binding promotes downstream activation of RHOA and phosphorylation of ERBB2 at 'Tyr-1248'. It required for normal brain development, axon guidance and cell migration, Probable signaling receptor which may play a role in myogenic differentiation through activation of the stress-activated MAPK cascade. |
| Species | Mouse |
| Expression System | HEK293 Cells |
| Tag | C-hFc |
| Accession Number | Q64151 |
| Amino Acid | Ala21-Gly664 |
| Construction | Ala21-Gly664 |
| Endotoxin | < 0.1 ng/µg (1 EU/µg) as determined by LAL test. |
| Formulation | Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS, pH 7.4. |
| Reconstitution | Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing. |
| Stability & Storage | Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots. |
| Shipping | In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice. |
| Synonyms | Semaphorin-C-like 1, Semaphorin-4C, Semaphorin I, Semai, Semacl1, Sema4c, Sema I, S4c, M-Sema F |
| Research Background |
| Molecular Weight | 115-125 KDa (reducing condition) |
| Storage | Lyophilized powder: -20~-80°C for 1 year | Solution: -80°C for 6 months |
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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Related Tags: SEMA4C Protein, Mouse, Recombinant (hFc) chemical structure | SEMA4C Protein, Mouse, Recombinant (hFc) molecular weight
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