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SEMA4C Protein, Mouse, Recombinant (hFc)

Catalog No. TMPJ-01176
Synonyms: M-Sema F, Semaphorin-C-like 1, Semai, Semaphorin I, Sema4c, Semacl1, Sema I, Semaphorin-4C, S4c

Semaphorin-4C is a protein which belongs to the semaphorin family, contains 1 Ig-like C2-type domain, 1 PSI domain, 1 Sema domain. As cell surface receptor for PLXNB2, it plays an important role in cell-cell signaling. PLXNB2 binding promotes downstream activation of RHOA and phosphorylation of ERBB2 at 'Tyr-1248'. It required for normal brain development, axon guidance and cell migration, Probable signaling receptor which may play a role in myogenic differentiation through activation of the stress-activated MAPK cascade.

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SEMA4C Protein, Mouse, Recombinant (hFc)
Pack Size Availability Price/USD Quantity
10 μg 5 days $ 184.00
50 μg 5 days $ 545.00
500 μg 5 days $ 1,900.00
1 mg 5 days $ 2,970.00
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Biological Description
Technical Params
Product Properties
Description Semaphorin-4C is a protein which belongs to the semaphorin family, contains 1 Ig-like C2-type domain, 1 PSI domain, 1 Sema domain. As cell surface receptor for PLXNB2, it plays an important role in cell-cell signaling. PLXNB2 binding promotes downstream activation of RHOA and phosphorylation of ERBB2 at 'Tyr-1248'. It required for normal brain development, axon guidance and cell migration, Probable signaling receptor which may play a role in myogenic differentiation through activation of the stress-activated MAPK cascade.
Species Mouse
Expression System Human Cells
Tag C-Fc
Accession Number Q64151
Synonyms M-Sema F, Semaphorin-C-like 1, Semai, Semaphorin I, Sema4c, Semacl1, Sema I, Semaphorin-4C, S4c
Amino Acid Ala21-Gly664
Construction Recombinant Mouse Semaphorin 4C is produced by our Mammalian expression system and the target gene encoding Ala21-Gly664 is expressed with a human IgG1 Fc tag at the C-terminus.
Molecular Weight 115-125 KDa, reducing conditions
Endotoxin Less than 0.1 ng/µg (1 EU/µg) as determined by LAL test.
Formulation Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
Reconstitution Always centrifuge tubes before opening.Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. 
Stability & Storage

Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months.

Shipping

The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature listed below.

Research Background Semaphorin-4C is a protein which belongs to the semaphorin family, contains 1 Ig-like C2-type domain, 1 PSI domain, 1 Sema domain. As cell surface receptor for PLXNB2, it plays an important role in cell-cell signaling. PLXNB2 binding promotes downstream activation of RHOA and phosphorylation of ERBB2 at 'Tyr-1248'. It required for normal brain development, axon guidance and cell migration, Probable signaling receptor which may play a role in myogenic differentiation through activation of the stress-activated MAPK cascade.

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Keywords

SEMA4C Protein, Mouse, Recombinant (hFc) M-Sema F Semaphorin-C-like 1 Semai Semaphorin I Sema4c Semacl1 Sema I Semaphorin-4C S4c recombinant recombinant-proteins proteins protein

 

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