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Anti-MMP-3 Antibody (9W229)

😃Good
Catalog No. TMAY-00865
Alias STR1, STMY1, STMY, SL-1, MMP-3, matrix metallopeptidase 3, CHDS6

Anti-MMP-3 Antibody (9W229) is a Mouse antibody targeting MMP-3. Anti-MMP-3 Antibody (9W229) can be used in ELISA(Cap).

Anti-MMP-3 Antibody (9W229)

Anti-MMP-3 Antibody (9W229)

😃Good
Catalog No. TMAY-00865Alias STR1, STMY1, STMY, SL-1, MMP-3, matrix metallopeptidase 3, CHDS6
Anti-MMP-3 Antibody (9W229) is a Mouse antibody targeting MMP-3. Anti-MMP-3 Antibody (9W229) can be used in ELISA(Cap).
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20 μL$69 7-10 days
100 μL$198 7-10 days
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Product Introduction

Bioactivity
Description
Anti-MMP-3 Antibody (9W229) is a Mouse antibody targeting MMP-3. Anti-MMP-3 Antibody (9W229) can be used in ELISA(Cap).
AliasSTR1, STMY1, STMY, SL-1, MMP-3, matrix metallopeptidase 3, CHDS6
Ig Type
Monoclonal Mouse IgG1
Clone
9W229
Reactivity
Human
Application
ELISA(Cap)
Antibody Type
Monoclonal
Host SpeciesMouse
ConstructionThis antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human MMP-3 (rh MMP-3; TMPY-02689; AAA36321.1; Tyr18-Thr272). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography.
PurificationProtein A
AppearanceLiquid
Formulation0.2 μm filtered solution in PBS
Research BackgroundMatrix metallopeptidase 3 (abbreviated as MMP3) is also known as stromelysin 1 and progelatinase. MMP3 is a member of the matrix metalloproteinase (MMP) family whose members are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, tissue remodeling, and disease processes including arthritis and metastasis. As a secreted zinc-dependent endopeptidase, MMP3 exerts its functions mainly in the extracellular matrix. This protein is activated by two major endogenous inhibitors: alpha2-macroglobulin and tissue inhibitors of metalloproteases (TIMPs). MMP3 plays a central role in degrading collagen types II, III, IV, IX, and X, proteoglycans, fibronectin, laminin, and elastin. Also, MMP3 can active other MMPs such as MMP1, MMP7, and MMP9, rendering MMP3 crucial in connective tissue remodeling. Dysregulation of MMPs has been implicated in many diseases including arthritis, chronic ulcers, encephalomyelitis, and cancer. Synthetic or natural inhibitors of MMPs result in inhibition of metastasis, while up-regulation of MMPs led to enhanced cancer cell invasion.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
Recombinant Human MMP-3 Protein (TMPY-02689)
Antigen Species
Human
Chemical Properties
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
TransportShipping with blue ice.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

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