SR-BI/SCARB1 Protein, Human, Recombinant (hFc)

Name: SR-BI/SCARB1 Protein, Human, Recombinant (hFc)
Brand: TargetMol
SKU: TMPY-05498
Rating: 4.5 (1 reviews)

(Synonyms: SR-BI, SRB1, scavenger receptor class B, member 1, HDLQTL6, CLA-1, CLA1, CD36L1) Copy Product Info

Synonyms: SR-BI, SRB1, scavenger receptor class B, member 1, HDLQTL6, CLA-1, CLA1, CD36L1

Catalog No. TMPY-05498 Copy Product Info

SR-BI/SCARB1 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 73.4 kDa and the accession number is Q8WTV0-5.

Pack Size	Price	EUR Stock	Global Stock
5 µg	52 €	7-10 days	7-10 days
10 µg	83 €	7-10 days	7-10 days
20 µg	136 €	7-10 days	7-10 days
50 µg	268 €	7-10 days	7-10 days
100 µg	519 €	7-10 days	7-10 days

For In stock only · Estimated delivery: EUR Stock (1-2 days) Global Stock (5-7 days)

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For research use only—not for human use. No sales to individuals. Use as intended only.

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User Guide of Recombinant Proteins

Product Information

Bioactivity

Bioactivity	Activity testing is in progress. It is theoretically active, but we cannot guarantee it. If you require protein activity, we recommend choosing the eukaryotic expression version first.
Description	SR-BI/SCARB1 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 73.4 kDa and the accession number is Q8WTV0-5.
Species	Human
Expression System	HEK293 Cells
Tag	C-hFc
Accession Number	Q8WTV0-5
Construction	A DNA sequence encoding the human SCARB1 ( NP_001076428.1) (Pro33-Tyr443) was expressed with the Fc region of human IgG1 at the C-terminus. Predicted N terminal: Pro 33
Protein Purity	> 90 % as determined by SDS-PAGE.
Endotoxin	< 1.0 EU/μg of the protein as determined by the LAL method.
Formulation	Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS, pH 7.4. Typically, a mixture containing 5% to 8% trehalose, mannitol, and 0.01% Tween 80 is incorporated as a protective agent before lyophilization.
Reconstitution	A Certificate of Analysis (CoA) containing reconstitution instructions is included with the products. Please refer to the CoA for detailed information.
Synonyms	SR-BI, SRB1, scavenger receptor class B, member 1, HDLQTL6, CLA-1, CLA1, CD36L1
Research Background	Scavenger receptor class B, member 1 (SCARB1), also known as CD36L1, is a member of the scavenger receptor family. SCARB1 is expressed primarily in liver and non placental steroidogenic tissues, and predominantly localized to cholesterol and sphingomyelin-enriched domains within the plasma membrane. SCARB1 is proposed as a receptor for different ligands such as phospholipids, cholesterol ester, lipoproteins, phosphatidylserine and apoptotic cells, and is involved in a wide variety of physilogical processes. As a key component in the reverse cholesterol transport pathway, SCARB1 binds high density lipoproteins (HDLs) and mediates selective cholesterol uptake by a mechanism distinct from the LDL pathway. High density lipoproteins (HDLs) play a critical role in cholesterol metabolism and their plasma concentrations are inversely correlated with risk for atherosclerosis. SCARB1 may thus serve as a useful marker that predicts variation in baseline lipid levels and postprandial lipid response. The mouse SCARB1 has been shown to exert actions in determining the levels of plasma lipoprotein cholesterol and the accumulation of cholesterol stores in the adrenal gland.

Chemical Properties

Molecular Weight

73.4 kDa (predicted)

Storage & Solubility Information

Shipping	In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice.
Storage	It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.