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Anti-USP6 Antibody (1Q774)
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Catalog No. TMAH-01240 Copy Product Info
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Anti-USP6 Antibody (1Q774) is a Mouse antibody targeting USP6. Anti-USP6 Antibody (1Q774) can be used in ELISA,IF,WB.
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 50 μL | $209 | 7-10 days | 7-10 days | |
| 100 μL | $349 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
Stability & Storage
| Description | Anti-USP6 Antibody (1Q774) is a Mouse antibody targeting USP6. Anti-USP6 Antibody (1Q774) can be used in ELISA,IF,WB. |
| Ig Type | IgG1 |
| Clone | 1Q774 |
| Reactivity | Human |
| Application | |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Subcellular Localization | Cell membrane. Cytoplasm. Endosome. Note=Localizes to the plasma membrane and to filamentous structures within the cell corresponding to ARF6 regulated tubular endosomes. Activation of RAC1 and CDC42 can direct the relocalization of USP6 to the plasma membrane in a manner that depends on the integrity of the actin cytoskeleton. |
| Tissue Specificity | Testis specific. Expressed in various cancer cell lines. |
| Construction | Hybridoma Monoclonal Antibody |
| Purification | Protein G purified |
| Appearance | Liquid |
| Formulation | Preservative: 0.03% Proclin 300. Constituents: 50% Glycerol, 0.01M PBS, PH 7.4. |
| Purity | >95% |
| Research Background | Deubiquitinase with an ATP-independent isopeptidase activity, cleaving at the C-terminus of the ubiquitin moiety. Catalyzes its own deubiquitination. In vitro, isoform 2, but not isoform 3, shows deubiquitinating activity. Promotes plasma membrane localization of ARF6 and selectively regulates ARF6-dependent endocytic protein trafficking. Is able to initiate tumorigenesis by inducing the production of matrix metalloproteinases following NF-kappa-B activation. |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Protein: Human Ubiquitin carboxyl-terminal hydrolase 6 Protein (348-535AA) |
| Antigen Species | Human |
| Gene Name | USP6 |
| Gene ID | |
| Uniprot ID | |
| Biology Area | Cell Biology |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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