STAT6 Protein, Human, Recombinant (Monomer, His)

Name: STAT6 Protein, Human, Recombinant (Monomer, His)
Brand: TargetMol
SKU: TMPY-07111
Rating: 4.5 (1 reviews)

(Synonyms: STAT6C, STAT6B, IL-4-STAT, HIES6, D12S1644) Copy Product Info

Synonyms: STAT6C, STAT6B, IL-4-STAT, HIES6, D12S1644

Catalog No. TMPY-07111 Copy Product Info

STAT6 Protein, Human, Recombinant (Monomer, His) is expressed in Baculovirus-Insect Cells. The accession number is P42226-1.

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Pack Size	Price	USA Stock	Global Stock
5 µg	$85	7-10 days	7-10 days
10 µg	$138	7-10 days	7-10 days
20 µg	$233	7-10 days	7-10 days
50 µg	$460	7-10 days	7-10 days
100 µg	$893	7-10 days	7-10 days
200 µg	$1,360	7-10 days	7-10 days
500 µg	$2,890	7-10 days	7-10 days
1 mg	$5,930	7-10 days	7-10 days

For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)

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For research use only—not for human use. No sales to individuals. Use as intended only.

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User Guide of Recombinant Proteins

Product Introduction

Bioactivity

Bioactivity	Activity testing is in progress. It is theoretically active, but we cannot guarantee it. If you require protein activity, we recommend choosing the eukaryotic expression version first.
Description	STAT6 Protein, Human, Recombinant (Monomer, His) is expressed in Baculovirus-Insect Cells. The accession number is P42226-1.
Species	Human
Expression System	Baculovirus Insect Cells
Tag	C-His
Accession Number	P42226-1
Construction	A DNA sequence encoding the human STAT6 isoform 1 (P42226-1) (Met1-Trp847) was fused with a polyhistidine tag at the C-terminus.
Protein Purity	≥ 90% as determined by SDS-PAGE. ≥ 90% as determined by SEC-HPLC.
Endotoxin	< 1.0 EU/μg of the protein as determined by the LAL method.
Formulation	Lyophilized from sterile 20 mM Tris, 500 mM NaCl, 20% Glycerol, 0.3 mM DTT, pH 7.4. Please contact us for any concerns or special requirements. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Reconstitution	Please refer to the lot-specific COA.
Synonyms	STAT6C, STAT6B, IL-4-STAT, HIES6, D12S1644
Research Background	Signal transducer and activator of transcription 6 (STAT6) is a transcription factor that is activated by interleukin-4 (IL-4)-induced tyrosine phosphorylation and mediates most of the IL-4-induced gene expression. STAT6 plays a central role in exerting interleukin-4 (IL-4) mediated biological responses and is found to induce the expression of BCL2L1/BCL-XL, which is responsible for the anti-apoptotic activity of IL4. Transcriptional activation by STAT6 requires the interaction with coactivators like p300 and the CREB-binding protein (CBP). NF-κB and tyrosine-phosphorylated Stat6 can directly bind each other in vitro and in vivo, which suggests that the direct interaction between Stat6 and NF-κB may provide a basis for synergistic activation of transcription by IL-4 and activators of NF-κB.

Chemical Properties

Molecular Weight

95.5 kDa (predicted); 97.6 kDa (reducing contition)

Storage & Solubility Information

Shipping	In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice.
Storage	It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.