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Beraprost sodium

Name: Beraprost sodium
Brand: TargetMol
SKU: T13859
Rating: 4.5 (1 reviews)

🥰Excellent

Catalog No. T13859Cas No. 496807-11-5

Beraprost sodium is a stable and orally active prodrug of PGI2.

Beraprost sodium

🥰Excellent

Catalog No. T13859Cas No. 496807-11-5

Beraprost sodium is a stable and orally active prodrug of PGI2.

Product information is being updated, if you want to purchase, please click the bulk custom button.

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Product Introduction

Bioactivity

Description	Beraprost sodium is a stable and orally active prodrug of PGI2.
In vitro	Beraprost sodium treatment leads to a significant increase in the number of tube formation, BPS plays an important role on angiogenic activity.
In vivo	Beraprost sodium oral adminstration can mitigate the development of renal interstitial fibrosis, decrease renal oxidative stress through its potential vasodilation effect, and further prevent renal interstitial fibrosis.

Chemical Properties

Molecular Weight	420.481
Formula	C₂₄H₂₉NaO₅
Cas No.	496807-11-5
Relative Density.	1.31g/cm3

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 250 mg/mL (594.56 mM), Sonication is recommended.

In Vivo Formulation

10% DMSO+40% PEG300+5% Tween-80+45% Saline: 3.3 mg/mL (7.85 mM), Sonication is recommeded.

Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	2.3782 mL	11.8911 mL	23.7823 mL	118.9114 mL
5 mM	0.4756 mL	2.3782 mL	4.7565 mL	23.7823 mL
10 mM	0.2378 mL	1.1891 mL	2.3782 mL	11.8911 mL
20 mM	0.1189 mL	0.5946 mL	1.1891 mL	5.9456 mL
50 mM	0.0476 mL	0.2378 mL	0.4756 mL	2.3782 mL
100 mM	0.0238 mL	0.1189 mL	0.2378 mL	1.1891 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc