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Octyl glucose neopentyl glycol

Name: Octyl glucose neopentyl glycol
Brand: TargetMol
SKU: T35879
Rating: 4.5 (1 reviews)

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Catalog No. T35879Cas No. 1257853-32-9

Octyl glucose neopentyl glycol (OGNG) is a detergent derived from neopentyl glycol, designed to stabilize membrane proteins [1].

Octyl glucose neopentyl glycol

🥰Excellent

Catalog No. T35879Cas No. 1257853-32-9

Octyl glucose neopentyl glycol (OGNG) is a detergent derived from neopentyl glycol, designed to stabilize membrane proteins [1].

Product information is being updated, if you want to purchase, please click the bulk custom button.

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Product Introduction

Bioactivity

Description	Octyl glucose neopentyl glycol (OGNG) is a detergent derived from neopentyl glycol, designed to stabilize membrane proteins [1].
In vitro	The significant advancement in enhancing the crystal quality of Thermotoga maritima (TmPPase) was achieved by substituting the detergent with Octyl glucose neopentyl glycol, a type of neopentyl glycol detergent[1].

Chemical Properties

Molecular Weight	568.701
Formula	C₂₇H₅₂O₁₂
Cas No.	1257853-32-9
Smiles	CCCCCCC(CCCCCC)(CO[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O)CO[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 250 mg/mL (439.6 mM), Sonication is recommended.

In Vivo Formulation

10% DMSO+40% PEG300+5% Tween-80+45% Saline: 5 mg/mL (8.79 mM), Sonication is recommended.

Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	1.7584 mL	8.7920 mL	17.5839 mL	87.9197 mL
5 mM	0.3517 mL	1.7584 mL	3.5168 mL	17.5839 mL
10 mM	0.1758 mL	0.8792 mL	1.7584 mL	8.7920 mL
20 mM	0.0879 mL	0.4396 mL	0.8792 mL	4.3960 mL
50 mM	0.0352 mL	0.1758 mL	0.3517 mL	1.7584 mL
100 mM	0.0176 mL	0.0879 mL	0.1758 mL	0.8792 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

Octyl glucose neopentyl glycol

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