Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Bis-sulfone-PEG4-DBCO is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
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Description | Bis-sulfone-PEG4-DBCO is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells. |
In vitro | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. |
Synonyms | Bis-sulfone-PEG4-DBCO |
Molecular Weight | 1006.2 |
Formula | C54H59N3O12S2 |
CAS No. | 1854034-70-0 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
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Bis-sulfone-PEG4-DBCO 1854034-70-0 Bis-sulfone-PEG-4-DBCO Bis sulfone PEG4 DBCO BissulfonePEG4DBCO inhibitor inhibit