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Anti-ESAM Antibody-APC (4F225)
🥰Excellent
Catalog No. TMAY-00424A
Anti-ESAM Antibody-APC (4F225) is a APC-conjugated Rabbit antibody targeting ESAM. Anti-ESAM Antibody-APC (4F225) can be used in FCM.
Anti-ESAM Antibody-APC (4F225)
Anti-ESAM Antibody-APC (4F225)
🥰Excellent
Catalog No. TMAY-00424A
Anti-ESAM Antibody-APC (4F225) is a APC-conjugated Rabbit antibody targeting ESAM. Anti-ESAM Antibody-APC (4F225) can be used in FCM.
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
| Description | Anti-ESAM Antibody-APC (4F225) is a APC-conjugated Rabbit antibody targeting ESAM. Anti-ESAM Antibody-APC (4F225) can be used in FCM. |
| Ig Type | Monoclonal Rabbit IgG |
| Clone | 4F225 |
| Reactivity | Human |
| Verified Activity | Profile of anti-ESAM reactivity on HUVEC cells analyzed by flow cytometry. |
| Application | FCM |
| Recommended Dose | 5 μl/Test, 0.1 mg/ml |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Construction | This antibody was obtained from a rabbit immunized with purified, recombinant Human ESAM (rh ESAM; TMPY-01312; NP_620411.2; Met 1-Ala 248) and conjugated with APC under optimum conditions, the unreacted APC was removed. |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | PBS solution containing 0.5% BSA and 0.09% sodium azide |
| Research Background | Endothelial cell-selective adhesion molecule (ESAM) is a member of JAM family of immunoglobulin superfamily and consists of one V-type and one C2-type immunoglobulin domain, as well as a hydrophobic signal sequence, a single transmembrane region, and a cytoplasmic domain. It is specifically expressed at endothelial tight junctions and on activated platelets. ESAM at endothelial tight junctions participates in the migration of neutrophils through the vessel wall, possibly by influencing endothelial cell contacts. The adaptor protein membrane-associated guanylate kinase MAGI-1 has been identified as an intracellular binding partner of ESAM. Previous studies have indicated that ESAM regulates angiogenesis in the primary tumor growth and endothelial permeability. It suggest that ESAM has a redundant functional role in physiological angiogenesis but serves a unique and essential role in pathological angiogenic processes such as tumor growth. |
| Conjucates | APC |
| Others Formats | Unconjugated/FITC/PE |
| Antibody Types Available | 4 |
| Immunogen | Recombinant Human ESAM protein (TMPY-01312) |
| Antigen Species | Human |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 12 months, do not freeze. Keep away from direct sunlight. Sodium azide is toxic to cells and should be disposed of properly. Flush with large volumes of water during disposal. |
| Transport | Shipping with blue ice. |
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For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . 
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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