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Anti-Carbonic Anhydrase VB Antibody (3I792)
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Catalog No. TMAY-02314
Alias MGC39962, CA-VB, carbonic anhydrase VB, mitochondrial
Anti-Carbonic Anhydrase VB Antibody (3I792) is a Rabbit antibody targeting Carbonic Anhydrase VB. Anti-Carbonic Anhydrase VB Antibody (3I792) can be used in IHC-P.
Anti-Carbonic Anhydrase VB Antibody (3I792)
Anti-Carbonic Anhydrase VB Antibody (3I792)
😃Good
Catalog No. TMAY-02314Alias MGC39962, CA-VB, carbonic anhydrase VB, mitochondrial
Anti-Carbonic Anhydrase VB Antibody (3I792) is a Rabbit antibody targeting Carbonic Anhydrase VB. Anti-Carbonic Anhydrase VB Antibody (3I792) can be used in IHC-P.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 100 μL | $268 | 7-10 days | 7-10 days |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
| Description | Anti-Carbonic Anhydrase VB Antibody (3I792) is a Rabbit antibody targeting Carbonic Anhydrase VB. Anti-Carbonic Anhydrase VB Antibody (3I792) can be used in IHC-P. |
| Synonyms | MGC39962, CA-VB, carbonic anhydrase VB, mitochondrial |
| Ig Type | Rabbit IgG |
| Clone | 3I792 |
| Reactivity | Human |
| Specificity | Human Carbonic Anhydrase VB Has cross-reactivity in ELISA with Human CA2 Human CA3 Human CA5A No cross-reactivity in ELISA with Human CA8 Human CA4 |
| Verified Activity | 1. Immunochemical staining of human CA5B in human placenta with rabbit monoclonal antibody (1:100, formalin-fixed paraffin embedded sections). 2. Immunochemical staining of human CA5B in human lung with rabbit monoclonal antibody (1:100, formalin-fixed paraffin embedded sections). 3. Immunochemical staining of human CA5B in human kidney with rabbit monoclonal antibody (1:100, formalin-fixed paraffin embedded sections). |
| Application | |
| Recommended Dose | IHC-P: 1:50-1:200 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Construction | This antibody was obtained from a rabbit immunized with purified, recombinant Human Carbonic Anhydrase VB / CA5B (rh Carbonic Anhydrase VB / CA5B; TMPY-02133; Q9Y2D0; Cys34-Pro317). |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | 0.2 μm filtered solution in PBS |
| Research Background | Carbonic anhydrase 5B, also known as carbonate dehydratase VB, carbonic anhydrase VB, CA-VB and CA5B, is amember of the alpha-carbonic anhydrase family. The strongest expression of CA5B / CA-VB is in heart, pancreas, kidney, placenta, lung, and skeletal muscle. It is not expressed in liver. Carbonic anhydrases (CAs) are a large family of zinc metalloenzymes first discovered in 1933 that catalyze the reversible hydration of carbon dioxide. CAs participate in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor, cerebrospinal fluid, saliva, and gastric acid. CAs show extensive diversity in tissue distribution and in their subcellular localization. CA5B / CA-VB is localized in the mitochondria and shows the highest sequence similarity to the other mitochondrial CA5A / CA-VA. CA5B / CA-VB has a wider tissue distribution than CA5A / CA-VA, which is restricted to the liver. The differences in tissue distribution suggest that the two mitochondrial carbonic anhydrases evolved to assume different physiologic roles. CA5A / CA-VA is activated by histamine, L-adrenaline, L- and D-histidine, and L- and D-phenylalanine. It is inhibited by coumarins, sulfonamide derivatives such as acetazolamide and Foscarnet (phosphonoformate trisodium salt). CA5B / CA-VB is inhibited by coumarins, sulfonamide derivatives such as acetazolamide (AZA), saccharin and Foscarnet (phosphonoformate trisodium salt). |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Protein: Human Carbonic Anhydrase VB / CA5B protein (TMPY-02133) |
| Antigen Species | Human |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| Transport | Shipping with blue ice. |
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