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Anti-Carboxypeptidase A2 Antibody (8W788) is a Mouse antibody targeting Carboxypeptidase A2. Anti-Carboxypeptidase A2 Antibody (8W788) can be used in ELISA(Cap),IHC-P.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
20 μL | $69 | 7-10 days | |
100 μL | $199 | 7-10 days |
Description | Antibody Type: Mouse Monoclonal Application: ELISA(Cap), IHC-P Reactivity: Human |
Alias | CPA2, carboxypeptidase A2 |
Ig Type | Mouse IgG2a |
Clone | 8W788 |
Reactivity | Human |
Verified Activity | Immunochemical staining of human CPA2 in human pancreas (from 2 donors) with mouse monoclonal antibody (1:60, formalin-fixed paraffin embedded sections). Positive staining was localized to pancreatic acinus. |
Application | ELISA(Cap),IHC-P |
Recommended Dose | IHC-P: 1:50-1:200; ELISA(Cap): 1:250-1:2000 |
Antibody Type | Monoclonal |
Host Species | Mouse |
Construction | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human Carboxypeptidase A2 / CPA2 (rh Carboxypeptidase A2 / CPA2; TMPY-00726; NP_001859.1; Met 1-Tyr 417). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography. |
Purification | Protein A |
Appearance | Liquid |
Formulation | 0.2 μm filtered solution in PBS |
Research Background | Carboxypeptidase A2 ( CPA2 ) is a secreted pancreatic procarboxy -peptidase, and cleaves the C-terminal amide or ester bond of peptides that have a free C-terminal carboxyl group. The hydrolytic action of CPA2 was identified with a preference towards long substrates with aromatic amino acids in their C-terminal end, particularly tryptophan. CPA2 comprises a signal peptide, a pro region and a mature chain, and can be activated after cleavage of the pro peptide. Three different forms of human pancreatic procarboxypeptidase A have been isolated, and the A1 and A2 forms are always secreted as monomeric proteins with different biochemical properties. |
Conjucates | Unconjugated |
Immunogen | Recombinant Protein: Human Carboxypeptidase A2 / CPA2 protein (TMPY-00726) |
Antigen Species | Human |
Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
Transport | Shipping with blue ice. |
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