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TGF beta 2 Protein, Human, Recombinant

Catalog No. TMPJ-00258
Synonyms: Glioblastoma-derived T-cell suppressor factor, TGF-β-2, Transforming growth factor β-2, Transforming growth factor beta-2, Cetermin, BSC-1 cell growth inhibitor, TGFB2, TGF-beta-2, Polyergin, G-TSF, TGF-β2

Transforming growth factor beta-2 (TGF-β2) is a secreted protein which belongs to the TGF-beta family. It is known as a cytokine that performs many cellular functions and has a vital role during embryonic development. The precursor is cleaved into mature TGF-beta-2 and LAP, which remains non-covalently linked to mature TGF-beta-2 rendering it inactive. It is an extracellular glycosylated protein. It is known to suppress the effects of interleukin dependent T-cell tumors. Defects in TGFB2 may be a cause of non-syndromic aortic disease (NSAD).

All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.
TGF beta 2 Protein, Human, Recombinant
Pack Size Availability Price/USD Quantity
10 μg In stock $ 118.00
50 μg 5 days $ 350.00
500 μg 5 days $ 2,360.00
1 mg 5 days $ 3,790.00
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Biological Description
Technical Params
Product Properties
Biological Information Measured by its ability to inhibit the IL-4-dependent proliferation of TF-1 cells. The ED50 for this effect is 30-180pg/ml. (QC verified)

Description Transforming growth factor beta-2 (TGF-β2) is a secreted protein which belongs to the TGF-beta family. It is known as a cytokine that performs many cellular functions and has a vital role during embryonic development. The precursor is cleaved into mature TGF-beta-2 and LAP, which remains non-covalently linked to mature TGF-beta-2 rendering it inactive. It is an extracellular glycosylated protein. It is known to suppress the effects of interleukin dependent T-cell tumors. Defects in TGFB2 may be a cause of non-syndromic aortic disease (NSAD).
Species Human
Expression System Human Cells
Tag None
Accession Number P61812
Synonyms Glioblastoma-derived T-cell suppressor factor, TGF-β-2, Transforming growth factor β-2, Transforming growth factor beta-2, Cetermin, BSC-1 cell growth inhibitor, TGFB2, TGF-beta-2, Polyergin, G-TSF, TGF-β2
Amino Acid Ala303-Ser414
Construction Recombinant Human Transforming Growth Factor Beta 2 is produced by our Mammalian expression system and the target gene encoding Ala303-Ser414 is expressed.
Protein Purity Greater than 95% as determined by reducing SDS-PAGE. (QC verified)

Molecular Weight 12 KDa, reducing conditions
Endotoxin Less than 0.001 ng/µg (0.01 EU/µg) as determined by LAL test.
Formulation Lyophilized from a 0.2 μm filtered solution of 4mM HCl.
Reconstitution Always centrifuge tubes before opening.Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. 
Stability & Storage

Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months.

Shipping

The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature listed below.

Research Background Transforming growth factor beta-2 (TGF-β2) is a secreted protein which belongs to the TGF-beta family. It is known as a cytokine that performs many cellular functions and has a vital role during embryonic development. The precursor is cleaved into mature TGF-beta-2 and LAP, which remains non-covalently linked to mature TGF-beta-2 rendering it inactive. It is an extracellular glycosylated protein. It is known to suppress the effects of interleukin dependent T-cell tumors. Defects in TGFB2 may be a cause of non-syndromic aortic disease (NSAD).

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Keywords

TGF beta 2 Protein, Human, Recombinant TGFB 2 TGF-b-2 Glioblastoma-derived T-cell suppressor factor TGF-β-2 Transforming growth factor β-2 Transforming growth factor beta-2 Cetermin TGFB-2 BSC-1 cell growth inhibitor Transforming growth factor b-2 TGFB2 TGF-beta-2 Polyergin G-TSF TGF-β2 recombinant recombinant-proteins proteins protein

 

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