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TGF beta 2 Protein, Human, Recombinant
(Synonyms: Transforming growth factor β-2, Transforming growth factor beta-2, TGF-β-2, TGF-β2, TGF-beta-2, TGFB2, Polyergin, G-TSF, Glioblastoma-derived T-cell suppressor factor, Cetermin, BSC-1 cell growth inhibitor) Copy Product InfoSynonyms: Transforming growth factor β-2, Transforming growth factor beta-2, TGF-β-2, TGF-β2, TGF-beta-2, TGFB2, Polyergin, G-TSF, Glioblastoma-derived T-cell suppressor factor, Cetermin, BSC-1 cell growth inhibitor
Catalog No. TMPJ-00258 Copy Product Info
Purity: 96.4%
Transforming growth factor beta-2 (TGF-β2) is a secreted protein which belongs to the TGF-beta family. It is known as a cytokine that performs many cellular functions and has a vital role during embryonic development. The precursor is cleaved into mature TGF-beta-2 and LAP, which remains non-covalently linked to mature TGF-beta-2 rendering it inactive. It is an extracellular glycosylated protein. It is known to suppress the effects of interleukin dependent T-cell tumors. Defects in TGFB2 may be a cause of non-syndromic aortic disease (NSAD).
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 5 μg | $74 | - | In Stock | |
| 10 μg | $118 | In Stock | In Stock | |
| 20 μg | $187 | 7-10 days | 7-10 days | |
| 50 μg | $350 | 7-10 days | 7-10 days | |
| 100 μg | $618 | 7-10 days | 7-10 days | |
| 200 μg | $1,090 | 7-10 days | 7-10 days | |
| 500 μg | $2,360 | 7-10 days | 7-10 days | |
| 1 mg | $3,790 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Purity:96.4%
Color:White
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Product Introduction
Bioactivity
Chemical Properties
Storage & Solubility Information
| Bioactivity | Measured by its ability to inhibit the IL-4-dependent proliferation of TF-1 cells. The ED50 for this effect is 30-180pg/ml. (QC verified)  |
| Description | Transforming growth factor beta-2 (TGF-β2) is a secreted protein which belongs to the TGF-beta family. It is known as a cytokine that performs many cellular functions and has a vital role during embryonic development. The precursor is cleaved into mature TGF-beta-2 and LAP, which remains non-covalently linked to mature TGF-beta-2 rendering it inactive. It is an extracellular glycosylated protein. It is known to suppress the effects of interleukin dependent T-cell tumors. Defects in TGFB2 may be a cause of non-syndromic aortic disease (NSAD). |
| Species | Human |
| Expression System | HEK293 Cells |
| Tag | Tag Free |
| Accession Number | P61812 |
| Amino Acid | Ala303-Ser414 |
| Construction | Ala303-Ser414 |
| Protein Purity | Greater than 95% as determined by reducing SDS-PAGE. (QC verified)  |
| Endotoxin | < 0.001 ng/µg (0.01 EU/µg) as determined by LAL test. |
| Formulation | Lyophilized from a solution filtered through a 0.22 μm filter, containing 4 mM HCl. |
| Reconstitution | Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing. |
| Stability & Storage | Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots. |
| Shipping | In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice. |
| Synonyms | Transforming growth factor β-2, Transforming growth factor beta-2, TGF-β-2, TGF-β2, TGF-beta-2, TGFB2, Polyergin, G-TSF, Glioblastoma-derived T-cell suppressor factor, Cetermin, BSC-1 cell growth inhibitor |
| Research Background |
| Molecular Weight | 12 KDa (reducing condition) |
| Storage | Lyophilized powder: -20~-80°C for 1 year | Solution: -80°C for 6 months |
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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Related Tags: TGF beta 2 Protein, Human, Recombinant chemical structure | TGF beta 2 Protein, Human, Recombinant molecular weight
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