HER3/ERBB3 Protein, Human, Recombinant (hFc)

Name: HER3/ERBB3 Protein, Human, Recombinant (hFc)
Brand: TargetMol
SKU: TMPY-00795
Rating: 4.5 (1 reviews)

(Synonyms: p85-sErbB3, p45-sErbB3, p180-ErbB3, MDA-BF-1, LCCS2, HER3, erbB3-S, ErbB-3, erb-b2 receptor tyrosine kinase 3, EEBB3, c-erbB-3, c-erbB3) Copy Product Info

Synonyms: p85-sErbB3, p45-sErbB3, p180-ErbB3, MDA-BF-1, LCCS2, HER3, erbB3-S, ErbB-3, erb-b2 receptor tyrosine kinase 3, EEBB3, c-erbB-3, c-erbB3

Catalog No. TMPY-00795 Copy Product Info

HER3/ERBB3 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 95.4 kDa and the accession number is P21860.

Pack Size	Price	USA Stock	Global Stock
5 µg	$38	7-10 days	7-10 days
10 µg	$59	7-10 days	7-10 days
20 µg	$95	7-10 days	7-10 days
50 µg	$172	7-10 days	7-10 days
100 µg	$348	7-10 days	7-10 days
200 µg	$519	7-10 days	7-10 days
500 µg	$1,120	7-10 days	7-10 days
1 mg	$2,290	7-10 days	7-10 days

For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)

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For research use only—not for human use. No sales to individuals. Use as intended only.

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User Guide of Recombinant Proteins

Product Information

Bioactivity

Bioactivity	Immobilized Human Her3, hFc Tag at 5 μg/ml (100 μl/well) on the plate. Dose response curve for Biotinylated Human NRG1 Beta 1, hFc Tag with the EC50 of 0.33 μg/ml determined by ELISA (QC Test). Immobilized Human Her3, hFc Tag at 1 μg/ml (100 μl/well) on the plate. Dose response curve for Biotinylated Anti-Her3 Antibody, hFc Tag with the EC50 of 10.7 ng/ml determined by ELISA.
Description	HER3/ERBB3 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 95.4 kDa and the accession number is P21860.
Species	Human
Expression System	HEK293 Cells
Tag	C-hFc
Accession Number	P21860
Construction	Ser20-Thr643
Protein Purity	> 95% as determined by Bis-Tris PAGE; > 95% as determined by HPLC
Endotoxin	< 1.0 EU/μg of the protein as determined by the LAL method.
Formulation	Lyophilized from 0.22μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution	Reconstitute the lyophilized protein in sterile deionized water. The product concentration should not be less than 100 μg/mL. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
Synonyms	p85-sErbB3, p45-sErbB3, p180-ErbB3, MDA-BF-1, LCCS2, HER3, erbB3-S, ErbB-3, erb-b2 receptor tyrosine kinase 3, EEBB3, c-erbB-3, c-erbB3
Research Background	Her3, also called ErbB3, is a type I membrane glycoprotein that is a member of the ErbB family of tyrosine kinase receptors.Her3 is expressed in keratinocytes, melanocytes, skeletal muscle cells, embryonic myoblasts and Schwann cells. Monomeric Her3 serves as a low affinity receptor for the heregulins (HRG).

Chemical Properties

Molecular Weight

95.4 kDa (predicted); 110-120 kDa (reducing condition, due to glycosylation)

Storage & Solubility Information

Shipping	In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice.
Storage	It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.