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PBRM1-BD2-IN-3

Name: PBRM1-BD2-IN-3
Brand: TargetMol
SKU: T60158
Price: 117 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T60158Cas No. 2819989-58-5

PBRM1-BD2-IN-3 (compound 12) is a potent PBRM1-BD2 inhibitor with an IC50 of 1.1 μM, used in anticancer research.

PBRM1-BD2-IN-3

🥰Excellent

Purity: 99.77%

Catalog No. T60158Cas No. 2819989-58-5

PBRM1-BD2-IN-3 (compound 12) is a potent PBRM1-BD2 inhibitor with an IC50 of 1.1 μM, used in anticancer research.

Pack Size	Price	Availability
1 mg	$117	In Stock
5 mg	$269	In Stock
10 mg	$395	In Stock
25 mg	$592	In Stock
50 mg	$834	In Stock
100 mg	$1,120	In Stock
500 mg	$2,260	In Stock
1 mL x 10 mM (in DMSO)	$238	In Stock

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Bulk & Custom

This molecule is a custom-made product. TargetMol has an excellent synthesis team with the experience and capability to provide you with cost-effective products. However, due to objective factors, there is a small probability that the synthesis may not be successful during the R&D process. We appreciate your understanding. If you have any questions, please feel free to contact us. We are committed to serving you wholeheartedly.

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Batch Information

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Purity:99.77%

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COA HNMR LCMS

Product Introduction

Bioactivity

Description

PBRM1-BD2-IN-3 (compound 12) is a potent PBRM1-BD2 inhibitor with an IC50 of 1.1 μM, used in anticancer research.

Chemical Properties

Molecular Weight	258.7
Formula	C₁₄H₁₁ClN₂O
Cas No.	2819989-58-5
Smiles	O=C1C=2C(NC(N1)C3=CC=CC=C3)=CC=CC2Cl
Relative Density.	1.287 g/cm3 (Predicted)

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 50 mg/mL (193.27 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	3.8655 mL	19.3274 mL	38.6548 mL	193.2741 mL
5 mM	0.7731 mL	3.8655 mL	7.7310 mL	38.6548 mL
10 mM	0.3865 mL	1.9327 mL	3.8655 mL	19.3274 mL
20 mM	0.1933 mL	0.9664 mL	1.9327 mL	9.6637 mL
50 mM	0.0773 mL	0.3865 mL	0.7731 mL	3.8655 mL
100 mM	0.0387 mL	0.1933 mL	0.3865 mL	1.9327 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc