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Description | Boc-NH-PEG7-acid, a PEG-based linker for PROTACs, connects two essential ligands crucial for PROTAC molecule formation, enabling selective protein degradation via the ubiquitin-proteasome system within cells. |
In vitro | PROTACs comprise two distinct ligands joined by a linker; one targets an E3 ubiquitin ligase, and the other targets the protein of interest. These compounds leverage the intracellular ubiquitin-proteasome system to selectively degrade target proteins [1]. |
Molecular Weight | 497.58 |
Formula | C22H43NO11 |
Cas No. | 2055044-68-1 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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