Contact UsQuotation
Shopping Cart
Remove All
  • TargetMol
    Your shopping cart is currently empty
Proceed to checkoutContinue shopping
TOPBioactivityChemical infoStorage&SolubilityCalculator

N-Formyl-Met-Leu-Phe-Lys

🥰Excellent
Catalog No. TP1168Cas No. 67247-11-4
Alias fMLFK

N-Formyl-Met-Leu-Phe-Lys (fMLFK) is a peptide that acts as a potent and selective agonist of FPR1, with EC50s of 3.5 nM for FPR1, 6.7 μM for FPR2, and 0.88 μM for FPR2-D2817.32G. This chemotactic peptide binds specifically to receptors on leukocyte membranes and its uptake can contribute to the quantitative assessment of neutrophils in localized inflammatory processes, independent of associated edema formation or microcirculatory compromise.

N-Formyl-Met-Leu-Phe-Lys

N-Formyl-Met-Leu-Phe-Lys

🥰Excellent
Purity: 99.7%
Catalog No. TP1168Alias fMLFKCas No. 67247-11-4
N-Formyl-Met-Leu-Phe-Lys (fMLFK) is a peptide that acts as a potent and selective agonist of FPR1, with EC50s of 3.5 nM for FPR1, 6.7 μM for FPR2, and 0.88 μM for FPR2-D2817.32G. This chemotactic peptide binds specifically to receptors on leukocyte membranes and its uptake can contribute to the quantitative assessment of neutrophils in localized inflammatory processes, independent of associated edema formation or microcirculatory compromise.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
1 mg$48In StockIn Stock
5 mg$107In StockIn Stock
10 mg$156In StockIn Stock
25 mg$258In StockIn Stock
50 mg$365In StockIn Stock
100 mg$491In StockIn Stock
200 mg$662In StockIn Stock
Add to Cart
Add to Quotation
In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.
Questions
TargetMol
View More

Batch Information

Select Batch
Purity:99.7%
Contact us for more batch information

Resource Download

COA HNMR LCMS

Product Introduction

Bioactivity
Description
N-Formyl-Met-Leu-Phe-Lys (fMLFK) is a peptide that acts as a potent and selective agonist of FPR1, with EC50s of 3.5 nM for FPR1, 6.7 μM for FPR2, and 0.88 μM for FPR2-D2817.32G. This chemotactic peptide binds specifically to receptors on leukocyte membranes and its uptake can contribute to the quantitative assessment of neutrophils in localized inflammatory processes, independent of associated edema formation or microcirculatory compromise.
Targets&IC50
FPR2 (D2817.32G):0.88 μM (EC50), FPR1:3.5 nM (EC50), FPR2:6.7 μM (EC50)
SynonymsfMLFK
Chemical Properties
Molecular Weight565.73
FormulaC27H43N5O6S
Cas No.67247-11-4
Smiles[C@@H](CC1=CC=CC=C1)(NC([C@@H](NC([C@H](CCSC)NC=O)=O)CC(C)C)=O)C(N[C@@H](CCCCN)C(O)=O)=O
Relative Density.1.193 g/cm3 (Predicted)
SequenceFormyl-Met-Leu-Phe-Lys
Sequence ShortFormyl-MLFK
Storage & Solubility Information
Storagekeep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
H2O: Soluble

Calculator

  • Molarity Calculator
  • Dilution Calculator
  • Reconstitution Calculator
  • Molecular Weight Calculator

In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.
1 Enter information below:
mg/kg
g
μL
2 Enter the in vivo formulation:
% DMSO
%
% Tween 80
% Saline/PBS/ddH2O

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

N-Formyl-Met-Leu-Phe-LysNFormylMetLeuPheLysN Formyl Met Leu Phe LysInhibitorinhibitFPR2FPR1
Related Tags: buy N-Formyl-Met-Leu-Phe-Lys | purchase N-Formyl-Met-Leu-Phe-Lys | N-Formyl-Met-Leu-Phe-Lys cost | order N-Formyl-Met-Leu-Phe-Lys | N-Formyl-Met-Leu-Phe-Lys chemical structure | N-Formyl-Met-Leu-Phe-Lys formula | N-Formyl-Met-Leu-Phe-Lys molecular weight
TargetMol | Logo

Copyright © 2015-2025 TargetMol Chemicals Inc. All Rights Reserved.