Sialidase-1 Protein, Human, Recombinant (His)

Name: Sialidase-1 Protein, Human, Recombinant (His)
Brand: TargetMol
SKU: TMPJ-01287
Rating: 4.5 (1 reviews)

(Synonyms: Sialidase-1, NEU1, NANH, N-Acetyl-α-Neuraminidase 1, N-Acetyl-Alpha-Neuraminidase 1, Lysosomal Sialidase, G9 Sialidase, Acetylneuraminyl Hydrolase) Copy Product Info

Synonyms: Sialidase-1, NEU1, NANH, N-Acetyl-α-Neuraminidase 1, N-Acetyl-Alpha-Neuraminidase 1, Lysosomal Sialidase, G9 Sialidase, Acetylneuraminyl Hydrolase

Catalog No. TMPJ-01287 Copy Product Info

Purity: 98%

Sialidase-1 belongs to the N-acetyl-a neuraminidase family. Sialidase-1 is expressed in many tissues; it is highly expressed in the pancreas, and weakly expressed in the brain. Sialidase-1 is a lysosomal enzyme, which cleaves terminal sialic acid residues from substrates such as glycoproteins and glycolipids. Deficiencies in the human enzyme Sialidase-1 leads to sialidosis, a rare lysosomal storage disease. Sialidase-1 has been shown to interact with Cathepsin A (protective protein), β-galactosidase and N-acetylgalactosamine-6-sulfate sulfatase in a multienzyme complex.

Sialidase-1 Protein, Human, Recombinant (His)

Pack Size	Price	USA Stock	Global Stock
10 µg	$183	7-10 days	7-10 days
20 µg	$292	7-10 days	7-10 days
50 µg	$545	7-10 days	7-10 days
100 µg	$792	7-10 days	7-10 days
200 µg	$1,150	7-10 days	7-10 days
500 µg	$1,900	7-10 days	7-10 days
1 mg	$2,730	7-10 days	7-10 days

For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)

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For research use only—not for human use. No sales to individuals. Use as intended only.

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Purity:98%

Color:Transparent

Resource Download

COA User Guide of Recombinant Proteins

Product Introduction

Bioactivity

Bioactivity	Activity has not been tested. It is theoretically active, but we cannot guarantee it. If you require protein activity, we recommend choosing the eukaryotic expression version first.
Description	Sialidase-1 belongs to the N-acetyl-a neuraminidase family. Sialidase-1 is expressed in many tissues; it is highly expressed in the pancreas, and weakly expressed in the brain. Sialidase-1 is a lysosomal enzyme, which cleaves terminal sialic acid residues from substrates such as glycoproteins and glycolipids. Deficiencies in the human enzyme Sialidase-1 leads to sialidosis, a rare lysosomal storage disease. Sialidase-1 has been shown to interact with Cathepsin A (protective protein), β-galactosidase and N-acetylgalactosamine-6-sulfate sulfatase in a multienzyme complex.
Species	Human
Expression System	HEK293 Cells
Tag	C-6xHis
Accession Number	Q99519
Amino Acid	Glu48-Leu415
Construction	Glu48-Leu415
Protein Purity	Greater than 95% as determined by reducing SDS-PAGE. (QC verified)
Endotoxin	< 0.1 ng/µg (1 EU/µg) as determined by LAL test.
Formulation	Supplied as a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, 50% Glycerol, pH 7.4.
Synonyms	Sialidase-1, NEU1, NANH, N-Acetyl-α-Neuraminidase 1, N-Acetyl-Alpha-Neuraminidase 1, Lysosomal Sialidase, G9 Sialidase, Acetylneuraminyl Hydrolase
Research Background	Sialidase-1 belongs to the N-acetyl-a neuraminidase family. Sialidase-1 is expressed in many tissues; it is highly expressed in the pancreas, and weakly expressed in the brain. Sialidase-1 is a lysosomal enzyme, which cleaves terminal sialic acid residues from substrates such as glycoproteins and glycolipids. Deficiencies in the human enzyme Sialidase-1 leads to sialidosis, a rare lysosomal storage disease. Sialidase-1 has been shown to interact with Cathepsin A (protective protein), β-galactosidase and N-acetylgalactosamine-6-sulfate sulfatase in a multienzyme complex.

Chemical Properties

Molecular Weight

39-50 KDa (reducing condition)

Storage & Solubility Information

Shipping	Proteins are shipped with blue ice.
Storage	Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.