NANS Protein, Human, Recombinant (His)

Catalog No. TMPJ-00520

Sialic Acid Synthase (NANS) is an enzyme that contains one AFP-like domain. NANS is ubiquitous and plays a role in the biosynthetic pathways of sialic acids. NANS produces N-acetylneuraminic acid (Neu5Ac) and 2-keto-3-deoxy-D-glycero-D-galacto-nononic acid (KDN). It also can use N-acetylmannosamine 6-phosphate and mannose 6-phosphate as substrates to generate phosphorylated forms of Neu5Ac and KDN, respectively.

NANS Protein, Human, Recombinant (His)

Catalog No. TMPJ-00520

Pack Size	Price	USA Warehouse	Global Warehouse
5 μg	$72	7-10 days	7-10 days
10 μg	$116	7-10 days	7-10 days
20 μg	$186	7-10 days	7-10 days
50 μg	$352	7-10 days	7-10 days
100 μg	$582	7-10 days	7-10 days
200 μg	$967	7-10 days	7-10 days
500 μg	$1,900	7-10 days	7-10 days
1 mg	$2,730	7-10 days	7-10 days

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In Stock Estimated shipping dateUSA Warehouse [1-2 days] Global Warehouse [5-7 days]

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Product Information

Biological Activity	Activity has not been tested. It is theoretically active, but we cannot guarantee it. If you require protein activity, we recommend choosing the eukaryotic expression version first.
Description	Sialic Acid Synthase (NANS) is an enzyme that contains one AFP-like domain. NANS is ubiquitous and plays a role in the biosynthetic pathways of sialic acids. NANS produces N-acetylneuraminic acid (Neu5Ac) and 2-keto-3-deoxy-D-glycero-D-galacto-nononic acid (KDN). It also can use N-acetylmannosamine 6-phosphate and mannose 6-phosphate as substrates to generate phosphorylated forms of Neu5Ac and KDN, respectively.
Species	Human
Expression System	E. coli
Tag	N-6xHis
Accession Number	AAH19315.1
Synonyms	Sialic Acid Synthase,SAS,NANS,N-Acetylneuraminic Acid Synthase,N-Acetylneuraminic Acid Phosphate Synthase,N-Acetylneuraminate-9-Phosphate Synthase,N-Acetylneuraminate Synthase
Amino Acid	Met1-Ser359
Construction	Met1-Ser359
Protein Purity	Greater than 80% as determined by reducing SDS-PAGE. (QC verified)
Molecular Weight	42 KDa (reducing condition)
Endotoxin	< 0.1 ng/µg (1 EU/µg) as determined by LAL test.
Formulation	Supplied as a 0.2 μm filtered solution of 20 mM Tris-HCl, 100 mM NaCl, pH 8.0.
Stability & Storage	Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.
Shipping	Shipping with blue ice.
Research Background	Sialic Acid Synthase (NANS) is an enzyme that contains one AFP-like domain. NANS is ubiquitous and plays a role in the biosynthetic pathways of sialic acids. NANS produces N-acetylneuraminic acid (Neu5Ac) and 2-keto-3-deoxy-D-glycero-D-galacto-nononic acid (KDN). It also can use N-acetylmannosamine 6-phosphate and mannose 6-phosphate as substrates to generate phosphorylated forms of Neu5Ac and KDN, respectively.

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