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NANS Protein, Human, Recombinant (His)

Catalog No. TMPJ-00520
Synonyms: N-Acetylneuraminic Acid Synthase, N-Acetylneuraminic Acid Phosphate Synthase, N-Acetylneuraminate-9-Phosphate Synthase, SAS, NANS, N-Acetylneuraminate Synthase, Sialic Acid Synthase

Sialic Acid Synthase (NANS) is an enzyme that contains one AFP-like domain. NANS is ubiquitous and plays a role in the biosynthetic pathways of sialic acids. NANS produces N-acetylneuraminic acid (Neu5Ac) and 2-keto-3-deoxy-D-glycero-D-galacto-nononic acid (KDN). It also can use N-acetylmannosamine 6-phosphate and mannose 6-phosphate as substrates to generate phosphorylated forms of Neu5Ac and KDN, respectively.

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NANS Protein, Human, Recombinant (His)
Pack Size Availability Price/USD Quantity
10 μg 5 days $ 116.00
50 μg 5 days $ 352.00
500 μg 5 days $ 1,900.00
1 mg 5 days $ 2,730.00
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Biological Description
Technical Params
Product Properties
Description Sialic Acid Synthase (NANS) is an enzyme that contains one AFP-like domain. NANS is ubiquitous and plays a role in the biosynthetic pathways of sialic acids. NANS produces N-acetylneuraminic acid (Neu5Ac) and 2-keto-3-deoxy-D-glycero-D-galacto-nononic acid (KDN). It also can use N-acetylmannosamine 6-phosphate and mannose 6-phosphate as substrates to generate phosphorylated forms of Neu5Ac and KDN, respectively.
Species Human
Expression System E. coli
Tag N-6His
Accession Number AAH19315.1
Synonyms N-Acetylneuraminic Acid Synthase, N-Acetylneuraminic Acid Phosphate Synthase, N-Acetylneuraminate-9-Phosphate Synthase, SAS, NANS, N-Acetylneuraminate Synthase, Sialic Acid Synthase
Amino Acid Met1-Ser359
Construction Recombinant Human N-Acetylneuraminate Synthase is produced by our E.coli expression system and the target gene encoding Met1-Ser359 is expressed with a 6His tag at the N-terminus.
Protein Purity Greater than 80% as determined by reducing SDS-PAGE. (QC verified)
Molecular Weight 42 KDa, reducing conditions
Endotoxin Less than 0.1 ng/µg (1 EU/µg) as determined by LAL test.
Formulation Supplied as a 0.2 μm filtered solution of 20mM Tris-HCl, 100mM NaCl, pH 8.0.
Stability & Storage

Store at ≤-70°C, stable for 6 months after receipt. Store at ≤-70°C, stable for 3 months under sterile conditions after opening. Please minimize freeze-thaw cycles.

Shipping

The product is shipped on dry ice/polar packs. Upon receipt, store it immediately at the temperature listed below.

Research Background Sialic Acid Synthase (NANS) is an enzyme that contains one AFP-like domain. NANS is ubiquitous and plays a role in the biosynthetic pathways of sialic acids. NANS produces N-acetylneuraminic acid (Neu5Ac) and 2-keto-3-deoxy-D-glycero-D-galacto-nononic acid (KDN). It also can use N-acetylmannosamine 6-phosphate and mannose 6-phosphate as substrates to generate phosphorylated forms of Neu5Ac and KDN, respectively.

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Keywords

NANS Protein, Human, Recombinant (His) N-Acetylneuraminic Acid Synthase N-Acetylneuraminic Acid Phosphate Synthase N-Acetylneuraminate-9-Phosphate Synthase SAS NANS N-Acetylneuraminate Synthase Sialic Acid Synthase recombinant recombinant-proteins proteins protein

 

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