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Anti-KRT5 Antibody (6Y466)

😃Good
Catalog No. TMAY-00124
Alias KRT5A, K5, EBS2F, EBS2E, EBS2D, EBS2C, EBS2B, EBS2A, EBS2, EBS1, DDD1, DDD, CK-5, CK5

Anti-KRT5 Antibody (6Y466) is a Rabbit antibody targeting KRT5. Anti-KRT5 Antibody (6Y466) can be used in IHC-P.

Anti-KRT5 Antibody (6Y466)

Anti-KRT5 Antibody (6Y466)

😃Good
Catalog No. TMAY-00124Alias KRT5A, K5, EBS2F, EBS2E, EBS2D, EBS2C, EBS2B, EBS2A, EBS2, EBS1, DDD1, DDD, CK-5, CK5
Anti-KRT5 Antibody (6Y466) is a Rabbit antibody targeting KRT5. Anti-KRT5 Antibody (6Y466) can be used in IHC-P.
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100 μL$268 7-10 days
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Product Introduction

Bioactivity
Description
Anti-KRT5 Antibody (6Y466) is a Rabbit antibody targeting KRT5. Anti-KRT5 Antibody (6Y466) can be used in IHC-P.
AliasKRT5A, K5, EBS2F, EBS2E, EBS2D, EBS2C, EBS2B, EBS2A, EBS2, EBS1, DDD1, DDD, CK-5, CK5
Ig Type
Monoclonal Rabbit IgG
Clone
6Y466
Reactivity
Human
Verified Activity
1. Immunochemical staining of human CK5 in human skin with rabbit monoclonal antibody (1:200, formalin-fixed paraffin embedded sections).

2. Immunochemical staining of human CK5 in human gastric cancer with rabbit monoclonal antibody (1:200, formalin-fixed paraffin embedded sections).

3. Immunochemical staining of human CK5 in human breast carcinoma with rabbit monoclonal antibody (1:200, formalin-fixed paraffin embedded sections).
Application
IHC-P
Recommended Dose
IHC-P: 1:100-1:500
Antibody Type
Monoclonal
Host SpeciesRabbit
ConstructionThis antibody was obtained from a rabbit immunized with a synthetic peptide corresponding to the center region of the human KRT5.
PurificationProtein A
AppearanceLiquid
Formulation0.2 μm filtered solution in PBS
Research BackgroundKeratin 5 is the major type II keratin of the basal cells of the epidermis and other stratified epithelia. With its type I partner, keratin 14, it constitutes a major fraction of the cytoskeleton of the basal cells. Epidermolysis bullosa simplex with mottled pigmentation (EBS-MP) is a rare dermatologic disorder of autosomal dominant inheritance with intraepidermal blistering after minor trauma, reticular hyperpigmentation unrelated to the blistering, nail dystrophy, and mild palmoplantar keratosis. Keratin 5 and keratin 14 are known to be essential for the basal keratinocyte cytoskeleton and are defective in several forms of epidermolysis bullosa simplex. Recently, a 71C-->T transition in the keratin 5 gene (KRT5) causing a P24L substitution was identified in some patients with EBS-MP.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
A synthetic peptide corresponding to the center region of the human KRT5
Antigen Species
Human
Chemical Properties
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
TransportShipping with blue ice.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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