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PKA Inhibitor Fragment (6-22) amide TFA

Catalog No. T75888

Synonyms: PKI-(6-22)-amide TFA, PKA Inhibitor Fragment (6-22) amide TFA(121932-06-7 Free base)

PKA Inhibitor Fragment (6-22) amide TFA (PKA Inhibitor Fragment (6-22) amide TFA) is an inhibitor of the highly potent cAMP-dependent protein kinase A (PKA) inhibitor (Ki: 2.8 nM).PKA Inhibitor Fragment (6-22) amide TFA reverses the pain-relieving effects of low levels of morphine in mice.

All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.

PKA Inhibitor Fragment (6-22) amide TFA Chemical Structure

PKA Inhibitor Fragment (6-22) amide TFA, CAS N/A

Pack Size	Availability	Price/USD	Quantity
1 mg	In stock	$ 125.00

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Purity: 99.61%

Biological Description

Chemical Properties

Storage & Solubility Information

Description	PKA Inhibitor Fragment (6-22) amide TFA (PKA Inhibitor Fragment (6-22) amide TFA) is an inhibitor of the highly potent cAMP-dependent protein kinase A (PKA) inhibitor (Ki: 2.8 nM).PKA Inhibitor Fragment (6-22) amide TFA reverses the pain-relieving effects of low levels of morphine in mice.
Targets&IC50	PKA:2.8 nM (Ki)

Synonyms	PKI-(6-22)-amide TFA, PKA Inhibitor Fragment (6-22) amide TFA(121932-06-7 Free base)
Molecular Weight	1982.08
Formula	C82H131F3N28O26

Storage

keep away from direct sunlight,keep away from moisture,store under nitrogen

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

H2O: 40 mg/mL, Sonication is recommended.

References and Literature

1. Dalton GD, et al. Alterations in brain Protein Kinase A activity and reversal of morphine tolerance by two fragments of native Protein Kinase A inhibitor peptide (PKI). Neuropharmacology. 2005 Apr; 48(5): 648-57. 2. Katz BM, et, al. Synthesis, characterization and inhibitory activities of (4-N3[3,5-3H]Phe10)PKI(6-22)amide and its precursors: photoaffinity labeling peptides for the active site of cyclic AMP-dependent protein kinase. Int J Pept Protein Res. 1989 Jun;33(6):439-45.

Related Products

Related compounds with same targets

AT7867 Gardenin A GUANOSINE 3':5'-CYCLIC MONOPHOSPHATE SOD Rottlerin CCT128930 hydrochloride PKA inhibitor fragment (6-22) amide Acetate Warangalone HA-1004

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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO (Master liquid concentration mg/mL)，Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation：Take μL DMSO master liquid, next add μL PEG300， mix and clarify, next add μL Tween 80，mix and clarify, next add μL ddH₂O, mix and clarify.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

PKA Inhibitor Fragment (6-22) amide TFA Tyrosine Kinase/Adaptors PKA PKI-(6-22)-amide TFA PKA Inhibitor Fragment (6-22) amide TFA(121932-06-7 Free base) inhibitor inhibit

Products are chemical reagents for research use only and are not intended for human use. We do not sell to patients.