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N-Arachidonyldopamine

Name: N-Arachidonyldopamine
Brand: TargetMol
SKU: T62530
Price: 44 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T62530Cas No. 199875-69-9

Alias NADA

N-Arachidonyldopamine (NADA) is a selective and potent endogenous CB1 receptor agonist (Ki: 250 nM).N-Arachidonyldopamine is also a potent and selective TRPV1 agonist with an EC50 value of ~50 nM.

N-Arachidonyldopamine

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Purity: 97.65%

Catalog No. T62530Alias NADACas No. 199875-69-9

N-Arachidonyldopamine (NADA) is a selective and potent endogenous CB1 receptor agonist (Ki: 250 nM).N-Arachidonyldopamine is also a potent and selective TRPV1 agonist with an EC50 value of ~50 nM.

Pack Size	Price	Availability
1 mg	$44	In Stock
5 mg	$98	In Stock
10 mg	$148	In Stock
25 mg	$249	In Stock
50 mg	$373	In Stock

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Purity:97.65%

Resource Download

COA HNMR HPLC

Product Introduction

Bioactivity

Description	N-Arachidonyldopamine (NADA) is a selective and potent endogenous CB1 receptor agonist (Ki: 250 nM).N-Arachidonyldopamine is also a potent and selective TRPV1 agonist with an EC50 value of ~50 nM.
Targets&IC50	CB1 receptor:250 nM (Ki), TRPV1:~50 nM (EC50)
Synonyms	NADA

Chemical Properties

Molecular Weight	439.63
Formula	C₂₈H₄₁NO₃
Cas No.	199875-69-9
Smiles	C(CNC(CCC/C=C\C/C=C\C/C=C\C/C=C\CCCCC)=O)C1=CC(O)=C(O)C=C1
Color	Yellow
Appearance	Oil

Storage & Solubility Information

Storage

keep away from direct sunlight,store at low temperature | Pure form: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 100 mg/mL (227.46 mM), Sonication is recommended.

Ethanol: 4.5 mg/mL (10.24 mM), Sonication is recommended.

In Vivo Formulation

10% DMSO+40% PEG300+5% Tween 80+45% Saline: 4 mg/mL (9.1 mM), Sonication is recommended.

Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.

Solution Preparation Table

Ethanol/DMSO

	1mg	5mg	10mg	50mg
1 mM	2.2746 mL	11.3732 mL	22.7464 mL	113.7320 mL
5 mM	0.4549 mL	2.2746 mL	4.5493 mL	22.7464 mL
10 mM	0.2275 mL	1.1373 mL	2.2746 mL	11.3732 mL

DMSO

	1mg	5mg	10mg	50mg
20 mM	0.1137 mL	0.5687 mL	1.1373 mL	5.6866 mL
50 mM	0.0455 mL	0.2275 mL	0.4549 mL	2.2746 mL
100 mM	0.0227 mL	0.1137 mL	0.2275 mL	1.1373 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc