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Desmethyl ferroquine

Name: Desmethyl ferroquine
Brand: TargetMol
SKU: T11006
Rating: 4.5 (1 reviews)

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Catalog No. T11006Cas No. 903546-18-9

Alias SSR97213

Desmethyl ferroquine is the active and major metabolite of Ferroquine.Desmethyl ferroquine shows significant activity against Chloroquine-susceptible and resistant P. falciparum strains. Ferroquine is an antimalarial.

Desmethyl ferroquine

🥰Excellent

Catalog No. T11006Alias SSR97213Cas No. 903546-18-9

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Product Introduction

Bioactivity

Description	Desmethyl ferroquine is the active and major metabolite of Ferroquine.Desmethyl ferroquine shows significant activity against Chloroquine-susceptible and resistant P. falciparum strains. Ferroquine is an antimalarial.
In vitro	Ferroquine's apparent terminal half-life is estimated to be 15.9 days. However, the main metabolite of the same activity, desmethyl ironquine (DMFQ), has a longer t1/2z, and the total average estimated time is 31.4 days.
Synonyms	SSR97213

Chemical Properties

Molecular Weight	419.73
Formula	C₂₂H₂₂ClFeN₃
Cas No.	903546-18-9
Smiles	C(NC=1C2=C(N=CC1)C=C(Cl)C=C2)[C-]34[Fe+2]56789%10%11(C3(CNC)=[CH]5[CH]6=[CH]74)[CH-]%12[CH]8=[CH]9[CH]%10=[CH]%11%12
Relative Density.	no data available

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 2.5 mg/mL (5.96 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	2.3825 mL	11.9124 mL	23.8248 mL	119.1242 mL
5 mM	0.4765 mL	2.3825 mL	4.7650 mL	23.8248 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline /PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline /PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc