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CD299 Protein, Human, Recombinant is expressed in HEK293 Cells. The accession number is Q9H2X3-1.

| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 5 μg | $93 | 7-10 days | 7-10 days | |
| 10 μg | $152 | 7-10 days | 7-10 days | |
| 20 μg | $248 | 7-10 days | 7-10 days | |
| 50 μg | $577 | 7-10 days | 7-10 days |
| Biological Activity | Activity has not been tested. It is theoretically active, but we cannot guarantee it. |
| Description | CD299 Protein, Human, Recombinant is expressed in HEK293 Cells. The accession number is Q9H2X3-1. |
| Species | Human |
| Expression System | HEK293 Cells |
| Tag | Tag Free |
| Accession Number | Q9H2X3-1 |
| Synonyms | MGC47866,MGC129964,L-SIGN,LSIGN,HP10347,DC-SIGNR,DCSIGNR,DC-SIGN2,C-type lectin domain family 4 member M,CLEC4M,CD299,CD209L |
| Construction | Gln71-Glu399 |
| Protein Purity | > 95% as determined by Bis-Tris PAGE;
> 95% as determined by HPLC |
| Molecular Weight | 37.72 kDa (Predicted); 38-50 kDa (Reducing conditions due to glycosylation) |
| Endotoxin | < 1.0 EU/μg of the protein as determined by the LAL method. |
| Formulation | Lyophilized from 0.22 μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization. |
| Reconstitution | Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing. |
| Stability & Storage | It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots. |
| Shipping | In general, Lyophilized powders are shipping with blue ice. |
| Research Background | CLEC4M, also known as DC-SIGNR, L-SIGN or CD209L, is a Ca2+-dependent C-type lectin. CLEC4M and its homologue DC-SIGN are encoded by the closely related lectin gene cluster on chromosome 19p13.3. higher expression of CLEC4M is associated with poor clinical prognosis in lung cancer patients and enhances the resistance of NSCLC cells to cisplatin. Inhibition of CLEC4M expression significantly increased cisplatin sensitivity, suggesting potential clinical significance for targeting CLEC4M in overcoming cisplatin resistance. |
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