Methyldopa hydrochloride

Name: Methyldopa hydrochloride
Brand: TargetMol
SKU: T15701
Rating: 4.5 (1 reviews)

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Catalog No. T15701Cas No. 884-39-9

Alias MK-351 hydrochloride, L-(-)-α-Methyldopa hydrochloride

L-(-)-α-Methyldopa hydrochloride is an alpha-adrenergic agonist psychoactive drug. It is used as a sympatholytic or antihypertensive. Methyldopa has a dual mechanism of action. It is a competitive inhibitor of the enzyme DOPA decarboxylase, which converts L-DOPA into dopamine.

Methyldopa hydrochloride

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Catalog No. T15701Alias MK-351 hydrochloride, L-(-)-α-Methyldopa hydrochlorideCas No. 884-39-9

Pack Size	Price	Availability
25 mg	$1,670	1-2 weeks
50 mg	$2,180	1-2 weeks
100 mg	$2,800	1-2 weeks

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Product Introduction

Bioactivity

Description	L-(-)-α-Methyldopa hydrochloride is an alpha-adrenergic agonist psychoactive drug. It is used as a sympatholytic or antihypertensive. Methyldopa has a dual mechanism of action. It is a competitive inhibitor of the enzyme DOPA decarboxylase, which converts L-DOPA into dopamine.
Synonyms	MK-351 hydrochloride, L-(-)-α-Methyldopa hydrochloride

Chemical Properties

Molecular Weight	247.68
Formula	C₁₀H₁₄ClNO₄
Cas No.	884-39-9
Relative Density.	1.31g/cm3

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

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For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

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