Shopping Cart
Remove All
Your shopping cart is currently empty
Epostane
Copy Product Info
😃Good
Catalog No. T68664Cas No. 80471-63-2
Alias Win-32729
Epostane acts as an antiprogestogen and terminates pregnancy by inhibiting 3β-hydroxysteroid dehydrogenase and preventing the biosynthesis of progesterone and pregnenolone. [4]
Epostane
Copy Product Info😃Good
Catalog No. T68664Alias Win-32729Cas No. 80471-63-2
Epostane acts as an antiprogestogen and terminates pregnancy by inhibiting 3β-hydroxysteroid dehydrogenase and preventing the biosynthesis of progesterone and pregnenolone. [4]
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 1 mg | $623 | In Stock | In Stock | |
| 5 mg | $1,290 | In Stock | In Stock | |
| 10 mg | $1,770 | In Stock | In Stock | |
| 25 mg | $2,630 | In Stock | In Stock | |
| 50 mg | $3,550 | In Stock | In Stock | |
| 100 mg | $4,790 | - | In Stock |
Add to Cart
Add to Quotation
In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
This molecule is a custom-made product. TargetMol has an excellent synthesis team with the experience and capability to provide you with cost-effective products.If you have any questions, please feel free to contact us. We are committed to serving you wholeheartedly.
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.
Batch Information
Select Batch
Purity:>99.99%
Appearance:Solid
Color:White
Contact us for more batch information
Product Introduction
Epostane AI Summary
Epostane shows antiviral activity against SARS-CoV-2 by inhibiting cytotoxicity in VERO-6 cells. The IC50 value for this compound is greater than 20,000 nM based on a high content imaging assay conducted after 48 hours of exposure to the virus..
Note: Summary generated by AI. Data source: ChEMBL 
Bioactivity
Chemical Properties
Storage & Solubility Information
| Description | Epostane acts as an antiprogestogen and terminates pregnancy by inhibiting 3β-hydroxysteroid dehydrogenase and preventing the biosynthesis of progesterone and pregnenolone. [4] |
| In vitro | METHODS: Using one fish oocyte, the ovary was cut into small pieces and incubated with Epostane (1 μg/mL), and the incidence of germinal vesicle breakdown (GVBD) was examined microscopically RESULTS Epostane induced a significant decrease in the frequency of GVBD in oocytes, but Epostane failed to eliminate the maturation effect of 17α,20 β-diOHprog, the most potent maturation-inducing steroid in this species. |
| In vivo | METHODS: A single-dose, randomized, double-blind study was conducted in which each woman awaiting termination of pregnancy was administered either 50 mg Epostane or 100 mg Epostane orally, and the effects of in vivo serum luteinizing hormone (P), estradiol (E2), and cortisol were determined. RESULTS Both serum P concentrations decreased significantly, and a similar decrease in serum E2 was observed, with subsequent normalization of E2. [1] METHODS: Seventy-eight healthy women were recruited to the study who were less than 49 days from their last menstrual period and requested termination of pregnancy, 200 mg Epostane four times daily for a total of 7 days. RESULTS The complete abortion rate in the Epostane group was 73%. [2] |
| Synonyms | Win-32729 |
| Molecular Weight | 357.49 |
| Formula | C22H31NO3 |
| Cas No. | 80471-63-2 |
| Smiles | C[C@@]12[C@]3([C@](C)(O3)C(O)=C(C#N)C1)CC[C@@]4([C@@]2(CC[C@@]5(C)[C@]4(CC[C@]5(C)O)[H])[H])[H] |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
Calculator
In Vivo Formulation Calculator (Clear solution)
Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:
For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, and a total of 10 animals are to be administered, using a formulation of 
10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH2O , the resulting working solution concentration would be 2 mg/mL.Stock Solution Preparation:
Dissolve 2 mg of the compound in 100 μL DMSO to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.
Preparation of the In Vivo Formulation:
1) Add 100 μL of the DMSO stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.
2) Add 50 μL Tween 80 and mix well until fully clarified.
3) Add 450 μL Saline,PBS or ddH2O and mix thoroughly until a homogeneous solution is obtained.
This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.
Dose Conversion
You can also refer to dose conversion for different animals. More Dose Conversion
Tech Support
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
Preview
Related Tags: buy Epostane | purchase Epostane | Epostane cost | order Epostane | Epostane chemical structure | Epostane in vivo | Epostane in vitro | Epostane formula | Epostane molecular weight
Generate Quote
Catalog No.: Cas No.:
Add
| Size | Quantity | Unit Price | Amount | Operation |
|---|
Generate Quote
- TOP
Feedback
Hello! How can I help you today? 
Copyright © 2015-2026 TargetMol Chemicals Inc. All Rights Reserved.