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Anti-CD46 Antibody (4K630)
😃Good
Catalog No. TMAY-02293
Alias TRA2.10, TLX, MIC10, MCP, CD46 molecule, complement regulatory protein, AHUS2
Anti-CD46 Antibody (4K630) is a Mouse antibody targeting CD46. Anti-CD46 Antibody (4K630) can be used in ELISA,IHC-P.
Anti-CD46 Antibody (4K630)
Anti-CD46 Antibody (4K630)
😃Good
Catalog No. TMAY-02293Alias TRA2.10, TLX, MIC10, MCP, CD46 molecule, complement regulatory protein, AHUS2
Anti-CD46 Antibody (4K630) is a Mouse antibody targeting CD46. Anti-CD46 Antibody (4K630) can be used in ELISA,IHC-P.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 100 μL | $199 | 7-10 days |
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
| Description | Antibody Type: Mouse Monoclonal Application: ELISA, IHC-P Reactivity: Human |
| Alias | TRA2.10, TLX, MIC10, MCP, CD46 molecule, complement regulatory protein, AHUS2 |
| Ig Type | Mouse IgG1 |
| Clone | 4K630 |
| Reactivity | Human |
| Verified Activity | Immunochemical staining of human CD46 in human placenta with mouse monoclonal antibody (1:60, formalin-fixed paraffin embedded sections). |
| Application | ELISA,IHC-P |
| Recommended Dose | ELISA: 1:1000-1:2000; IHC-P: 1:50-1:200 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human CD46 (rh CD46; TMPY-02023; EAW93471.1; Met 1-Asp 328). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography. |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | 0.2 μm filtered solution in PBS |
| Research Background | CD46, also known as Membrane Cofactor Protein (MCP), is a complement regulatory protein. CD46 is a type 1 membrane protein that plays an important inhibitory role in the complement system. CD46 is expressed in white blood cells, platelets, epithelial cells, and fibroblasts. Human CD46 shares 5% amino acid sequence identity with mouse and rat CD46. The importance of CD46 to complement regulation is underscored by the observation that genetic loss of CD46 leads to development of atypical hemolytic-uremic syndrome (aHUS), a disease characterized by uncontrolled complement activation. CD46 is implicated in the development and/or progression of selected cancer types. |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Protein: Human CD46 protein (TMPY-02023) |
| Antigen Species | Human |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| Transport | Shipping with blue ice. |
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For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . 
Tech Support
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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