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Anti-HLA-DPB1 Antibody (7X876) (Synonyms: MHC class II antigen DPB1, HLA-DPB1, HLA-DP1B, HLA class II histoco...)

Catalog No. TMAC-02581 Copy Product Info
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Anti-HLA-DPB1 Antibody (7X876) is a Rabbit antibody targeting HLA-DPB1. Anti-HLA-DPB1 Antibody (7X876) can be used in ICC/IF,IHC,IP,WB.

Anti-HLA-DPB1 Antibody (7X876)

Copy Product Info
🥰Excellent
Catalog No. TMAC-02581
Synonyms MHC class II antigen DPB1, HLA-DPB1, HLA-DP1B, HLA class II histocompatibility antigen, DP(W4) beta chain, HLA class II histocompatibility antigen, DP beta 1 chain, DP beta 1 chain

Anti-HLA-DPB1 Antibody (7X876) is a Rabbit antibody targeting HLA-DPB1. Anti-HLA-DPB1 Antibody (7X876) can be used in ICC/IF,IHC,IP,WB.

Anti-HLA-DPB1 Antibody
(7X876)
Pack SizePriceUSA StockGlobal StockQuantity
50 μL$2977-10 days7-10 days
100 μL$4987-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-HLA-DPB1 Antibody (7X876) is a Rabbit antibody targeting HLA-DPB1. Anti-HLA-DPB1 Antibody (7X876) can be used in ICC/IF,IHC,IP,WB.
SynonymsMHC class II antigen DPB1, HLA-DPB1, HLA-DP1B, HLA class II histocompatibility antigen, DP(W4) beta chain, HLA class II histocompatibility antigen, DP beta 1 chain, DP beta 1 chain
Ig Type
IgG
Clone
7X876
Reactivity
Human
Verified Activity
1. Immunohistochemical analysis of paraffin-embedded human tonsil tissue using anti- MHC Class II antibody. Counter stained with hematoxylin.
2. Immunohistochemical analysis of paraffin-embedded human spleen tissue using anti- MHC Class II antibody. Counter stained with hematoxylin.
verifiedActivityverifiedActivity
Application
Recommended Dose
WB: 1:500-1000; IHC: 1:50-200; ICC/IF: 1:50-100; IP: 1:10-50
Antibody Type
Monoclonal
Host SpeciesRabbit
ConstructionRecombinant Antibody
PurificationProA affinity purified
AppearanceLiquid
Formulation1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
Research BackgroundMajor histocompatibility complex (MHC) molecules, also designated human leukocyte antigen (HLA) molecules, are cell-surface receptors that bind foreign peptides and present them to T lymphocytes. MHC class I molecules consist of two polypeptide chains, an α or heavy chain and β-2-Microglobulin, a non-covalently associated protein. Cytotoxic T lymphocytes bind antigenic peptides presented by MHC class I molecules. Antigens that bind to MHC class I molecules are typically eight to ten residues in length and are stabilized in a peptide binding groove. MHC class II molecules are encoded by polymorphic MHC genes and consist of a non-covalent complex of an α and β chain. Helper T lymphocytes bind antigenic peptides presented by MHC class II molecules. MHC class II molecules bind 13-18 amino acid antigenic peptides. Accumu-lating in endosomal/lysosomal compartments and on the surface of B cells, HLA-DM and -DO molecules regulate binding of exogenous peptides to class II molecules (HLA-DR) by sustaining a conformation that favors peptide exchange. The differential structural properties of MHC class I and class II molecules account for their respective roles in activating different populations of T lymphocytes.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
Recombinant Protein
Uniprot ID
Chemical Properties
Molecular WeightTheoretical: 29 kDa.
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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