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M-CSF/CSF1 Protein, Human, Recombinant (His)

(Synonyms: M-CSF, MCSF, Macrophage Colony-Stimulating Factor 1, Lanimostim, CSF-1, CSF1) Copy Product Info

Synonyms: M-CSF, MCSF, Macrophage Colony-Stimulating Factor 1, Lanimostim, CSF-1, CSF1

Catalog No. TMPJ-00327 Copy Product Info
Macrophage Colony-Stimulating Factors (m-csf) are cytokines that act in hematopoiesis by controlling the production, differentiation, and function of 2 related white cell populations of the blood, the granulocytes and themonocytes-macrophages. CSF-1 promotes the release of proinflammatory chemokines, and thereby plays an important role in innate immunity and in inflammatory processes. It also plays an important role in the regulation of osteoclast proliferation and differentiation, the regulation of bone resorption, and is required for normal bone development. CSF-1 is required for normal male and female fertility and promotes reorganization of the actin cytoskeleton, regulates formation of membrane ruffles, cell adhesion and cell migration. it also plays a role in lipoprotein clearance.
Pack SizePriceUSA StockGlobal StockQuantity
5 μg$74-In Stock
10 μg$118-In Stock
20 μg$187-In Stock
50 μg$350-In Stock
100 μg$613-In Stock
200 μg$1,0707-10 days7-10 days
500 μg$2,2907-10 days7-10 days
1 mg$3,2707-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Batch Information

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Purity:Greater than 95% as determined by reducing SDS-PAGE.
Appearance:Lyophilized powder
Color:White
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Product Introduction

Bioactivity
Description
Macrophage Colony-Stimulating Factors (m-csf) are cytokines that act in hematopoiesis by controlling the production, differentiation, and function of 2 related white cell populations of the blood, the granulocytes and themonocytes-macrophages. CSF-1 promotes the release of proinflammatory chemokines, and thereby plays an important role in innate immunity and in inflammatory processes. It also plays an important role in the regulation of osteoclast proliferation and differentiation, the regulation of bone resorption, and is required for normal bone development. CSF-1 is required for normal male and female fertility and promotes reorganization of the actin cytoskeleton, regulates formation of membrane ruffles, cell adhesion and cell migration. it also plays a role in lipoprotein clearance.
Species
Human
Expression System
HEK293 Cells
TagC-6xHis
Accession NumberP09603
Amino AcidGlu33-Arg255
ConstructionGlu33-Arg255
Protein Purity
Greater than 95% as determined by reducing SDS-PAGE. (QC verified)
https://cdn.targetmol.com/group3/M00/12/EE/CgoaEGZG0zSET5vQAAAAAG1FJK0390.png
Endotoxin< 0.001 ng/µg (0.01 EU/µg) as determined by LAL test.
FormulationLyophilized from a 0.2 μm filtered solution of 20mM PB,150mM NaCl,4% Mannitol,pH 7.2.
ReconstitutionReconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
Stability & StorageLyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.
ShippingIn general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice.
SynonymsM-CSF, MCSF, Macrophage Colony-Stimulating Factor 1, Lanimostim, CSF-1, CSF1
Research Background
Chemical Properties
Molecular Weight41 KDa (reducing condition)
Storage & Solubility Information
StorageStore at low temperature Lyophilized powder: -20~-80°C for 1 year | Solution: -80°C for 6 months

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

Related Tags: M-CSF/CSF1 Protein, Human, Recombinant (His) chemical structure | M-CSF/CSF1 Protein, Human, Recombinant (His) molecular weight