M-CSF/CSF1 Protein, Human, Recombinant (His)

Name: M-CSF/CSF1 Protein, Human, Recombinant (His)
Brand: TargetMol
SKU: TMPJ-00327
Price: 74 USD
Availability: InStock
Rating: 5 (10 reviews)

(Synonyms: M-CSF, MCSF, Macrophage Colony-Stimulating Factor 1, Lanimostim, CSF-1, CSF1) Copy Product Info

Synonyms: M-CSF, MCSF, Macrophage Colony-Stimulating Factor 1, Lanimostim, CSF-1, CSF1

Catalog No. TMPJ-00327 Copy Product Info

Macrophage Colony-Stimulating Factors (m-csf) are cytokines that act in hematopoiesis by controlling the production, differentiation, and function of 2 related white cell populations of the blood, the granulocytes and themonocytes-macrophages. CSF-1 promotes the release of proinflammatory chemokines, and thereby plays an important role in innate immunity and in inflammatory processes. It also plays an important role in the regulation of osteoclast proliferation and differentiation, the regulation of bone resorption, and is required for normal bone development. CSF-1 is required for normal male and female fertility and promotes reorganization of the actin cytoskeleton, regulates formation of membrane ruffles, cell adhesion and cell migration. it also plays a role in lipoprotein clearance.

M-CSF/CSF1 Protein, Human, Recombinant (His)

Pack Size	Price	USA Stock	Global Stock
5 µg	$74	-	In Stock
10 µg	$118	-	In Stock
20 µg	$187	-	In Stock
50 µg	$350	-	In Stock
100 µg	$613	-	In Stock
200 µg	$1,070	7-10 days	7-10 days
500 µg	$2,290	7-10 days	7-10 days
1 mg	$3,270	7-10 days	7-10 days

For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)

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For research use only—not for human use. No sales to individuals. Use as intended only.

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Purity:Greater than 95% as determined by reducing SDS-PAGE.

Appearance:Lyophilized powder

Color:White

Resource Download

COA User Guide of Recombinant Proteins

Product Introduction

Bioactivity

Bioactivity	easured in a cell proliferation assay using M-NFS-60 mouse lymphoblast cells.The ED50 for this effect is 2-10 ng/mL. (QC verified)
Description	Macrophage Colony-Stimulating Factors (m-csf) are cytokines that act in hematopoiesis by controlling the production, differentiation, and function of 2 related white cell populations of the blood, the granulocytes and themonocytes-macrophages. CSF-1 promotes the release of proinflammatory chemokines, and thereby plays an important role in innate immunity and in inflammatory processes. It also plays an important role in the regulation of osteoclast proliferation and differentiation, the regulation of bone resorption, and is required for normal bone development. CSF-1 is required for normal male and female fertility and promotes reorganization of the actin cytoskeleton, regulates formation of membrane ruffles, cell adhesion and cell migration. it also plays a role in lipoprotein clearance.
Species	Human
Expression System	HEK293 Cells
Tag	C-6xHis
Accession Number	P09603
Amino Acid	Glu33-Arg255
Construction	Glu33-Arg255
Protein Purity	Greater than 95% as determined by reducing SDS-PAGE. (QC verified)
Endotoxin	< 0.001 ng/µg (0.01 EU/µg) as determined by LAL test.
Formulation	Lyophilized from a 0.2 μm filtered solution of 20mM PB，150mM NaCl，4% Mannitol，pH 7.2.
Reconstitution	Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
Synonyms	M-CSF, MCSF, Macrophage Colony-Stimulating Factor 1, Lanimostim, CSF-1, CSF1
Research Background	Macrophage Colony-Stimulating Factors (m-csf) are cytokines that act in hematopoiesis by controlling the production, differentiation, and function of 2 related white cell populations of the blood, the granulocytes and themonocytes-macrophages. CSF-1 promotes the release of proinflammatory chemokines, and thereby plays an important role in innate immunity and in inflammatory processes. It also plays an important role in the regulation of osteoclast proliferation and differentiation, the regulation of bone resorption, and is required for normal bone development. CSF-1 is required for normal male and female fertility and promotes reorganization of the actin cytoskeleton, regulates formation of membrane ruffles, cell adhesion and cell migration. it also plays a role in lipoprotein clearance.

Chemical Properties

Molecular Weight

41 KDa (reducing condition)

Storage & Solubility Information

Shipping	In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice.
Storage	Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.