LMCD1 Protein, Human, Recombinant (His)

Name: LMCD1 Protein, Human, Recombinant (His)
Brand: TargetMol
SKU: TMPJ-01364
Rating: 4.5 (1 reviews)

(Synonyms: LMCD1, LIM and cysteine-rich domains protein 1, Dyxin) Copy Product Info

Synonyms: LMCD1, LIM and cysteine-rich domains protein 1, Dyxin

Catalog No. TMPJ-01364 Copy Product Info

LMCD1 is transcriptional cofactor which contains a cysteine-rich domain in the N-terminal region and 2 LIM domains in the C-terminal region. It also has several potential phosphorylation and N-myristoylation sites and a single potential N-glycosylation site. LMCD1 is expressed in many tissues with highest abundance in skeletal muscle. LMCD1 restricts GATA6 function by inhibiting DNA-binding, resulting in repression of GATA6 transcriptional activation of downstream target genes. It plays a critical role in the development of cardiac hypertrophy via activation of calcineurin/nuclear factor of activated T-cells signaling pathway.

Customer service consultation

Pack Size	Price	USA Stock	Global Stock
5 μg	$112	35 days	35 days
10 μg	$183	35 days	35 days
20 μg	$292	35 days	35 days
50 μg	$545	35 days	35 days
100 μg	$813	35 days	35 days
200 μg	$1,190	35 days	35 days
500 μg	$2,070	35 days	35 days
1 mg	$2,970	35 days	35 days

For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)

Add to Cart

Add to Quotation

For research use only—not for human use. No sales to individuals. Use as intended only.

Questions

Resource Download

User Guide of Recombinant Proteins

Product Introduction

Bioactivity

Bioactivity	Activity has not been tested. It is theoretically active, but we cannot guarantee it. If you require protein activity, we recommend choosing the eukaryotic expression version first.
Description	LMCD1 is transcriptional cofactor which contains a cysteine-rich domain in the N-terminal region and 2 LIM domains in the C-terminal region. It also has several potential phosphorylation and N-myristoylation sites and a single potential N-glycosylation site. LMCD1 is expressed in many tissues with highest abundance in skeletal muscle. LMCD1 restricts GATA6 function by inhibiting DNA-binding, resulting in repression of GATA6 transcriptional activation of downstream target genes. It plays a critical role in the development of cardiac hypertrophy via activation of calcineurin/nuclear factor of activated T-cells signaling pathway.
Species	Human
Expression System	E. coli
Tag	N, C-6xHis
Accession Number	Q9NZU5
Amino Acid	Met1-Ser365
Construction	Met1-Ser365
Protein Purity	Greater than 95% as determined by reducing SDS-PAGE. (QC verified)
Endotoxin	< 0.1 ng/µg (1 EU/µg) as determined by LAL test.
Formulation	Supplied as a 0.2 μm filtered solution of 20 mM Tris-HCl, 150 mM NaCl, 1 mM EDTA, pH 8.0.
Stability & Storage	Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.
Shipping	Proteins are shipped with blue ice.
Synonyms	LMCD1, LIM and cysteine-rich domains protein 1, Dyxin
Research Background

Chemical Properties

Molecular Weight

45 KDa (reducing condition)

Storage & Solubility Information

Storage

Store at low temperature Lyophilized powder: -20~-80°C for 1 year | Solution: -80°C for 6 months

Calculator

Molarity Calculator
Dilution Calculator
Reconstitution Calculator
Molecular Weight Calculator

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

LMCD-1LMCD 1

Related Tags: LMCD1 Protein, Human, Recombinant (His) chemical structure | LMCD1 Protein, Human, Recombinant (His) molecular weight