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Anti-Phospho-PAK1/2/3 (Thr423/402/421) Polyclonal Antibody

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Catalog No. TMAC-03053

Anti-Phospho-PAK1/2/3 (Thr423/402/421) Polyclonal Antibody is a Rabbit antibody targeting Phospho-PAK1/2/3 (Thr423/402/421). Anti-Phospho-PAK1/2/3 (Thr423/402/421) Polyclonal Antibody can be used in IHC,IF.

Anti-Phospho-PAK1/2/3 (Thr423/402/421) Polyclonal Antibody

Anti-Phospho-PAK1/2/3 (Thr423/402/421) Polyclonal Antibody

😃Good
Catalog No. TMAC-03053
Anti-Phospho-PAK1/2/3 (Thr423/402/421) Polyclonal Antibody is a Rabbit antibody targeting Phospho-PAK1/2/3 (Thr423/402/421). Anti-Phospho-PAK1/2/3 (Thr423/402/421) Polyclonal Antibody can be used in IHC,IF.
Pack SizePriceAvailabilityQuantity
50 μL$2167-10 days
100 μL$3167-10 days
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Product Introduction

Bioactivity
Description
Anti-Phospho-PAK1/2/3 (Thr423/402/421) Polyclonal Antibody is a Rabbit antibody targeting Phospho-PAK1/2/3 (Thr423/402/421). Anti-Phospho-PAK1/2/3 (Thr423/402/421) Polyclonal Antibody can be used in IHC,IF.
Ig Type
IgG
Reactivity
Human,Mouse,Rat
Application
Antibody Type
Polyclonal
Host SpeciesRabbit
ConstructionPolyclonal Antibody
PurificationAntibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.
AppearanceLiquid
FormulationSupplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Research BackgroundThe activated kinase acts on a variety of targets. Likely to be the GTPase effector that links the Rho-related GTPases to the JNK MAP kinase pathway. Activated by CDC42 and RAC1. Involved in dissolution of stress fibers and reorganization of focal complexes. Involved in regulation of microtubule biogenesis through phosphorylation of TBCB. Activity is inhibited in cells undergoing apoptosis, potentially due to binding of CDC2L1 and CDC2L2.
Related Conjugates and Formulations
Conjucates
Unconjugated
Others Formats
Phospho
Antigen Details
Immunogen
Peptide sequence around phosphorylation site of threonine 423 /402/421 (R-S-T(p)-M-V) derived from Human PAK1/PAK2/PAK3
Antigen Species
human
Uniprot ID
Chemical Properties
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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