Kirsten rat sarcoma 2 viral oncogene homolog (KRAS) is the most commonly mutated oncogene in human cancer. The developments of many cancers depend on sustained expression and signaling of KRAS, which makes KRAS a high-priority therapeutic target.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
100 μg | Inquiry | $ 734.00 | |
1 mg | Inquiry | $ 4,899.00 |
Description | Kirsten rat sarcoma 2 viral oncogene homolog (KRAS) is the most commonly mutated oncogene in human cancer. The developments of many cancers depend on sustained expression and signaling of KRAS, which makes KRAS a high-priority therapeutic target. |
Species | Human |
Expression System | HEK293 |
Tag | C-His-Avi |
Accession Number | AAV53343.1(HLA-A*11:01)&P61769(B2M)&VVVGAGGVGK |
Synonyms | RASK2, KRAS2, KRAS1, MHC, C-K-RAS, KI-RAS, K-RAS4B, RALD, K-RAS4A, NS3, KRAS, NS, GTPase Kras, K-Ras 2, K-RAS2A, CFC2, K-RAS2B |
Construction | Recombinant PE-Labeled Human HLA-A*11:01&B2M&KRAS WT (VVVGAGGVGK) Tetramer Protein is expressed from HEK293 with His tag and Avi tag at the C-Terminus. PE-labeled Human HLA-A*11:01&B2M&KRAS WT (VVVGAGGVGK) Tetramer is assembled by biotinylated monomer and PE-Labeled streptavidin. It contains Gly25-Thr305(HLA-A*11:01), Ile21-Met119(B2M) and VVVGAGGVGK peptide.[Accession |AAV53343.1(HLA-A*11:01)&P61769(B2M)&VVVGAGGVGK] |
Endotoxin | Less than 1EU per μg by the LAL method. |
Formulation | Supplied as 0.22μm filtered solution in PBS, 0.2% BSA (pH 7.4). |
Stability & Storage |
Valid for 6 months from date of receipt when stored at -80°C.Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
Shipping |
In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature.Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise. |
Research Background | Kirsten rat sarcoma 2 viral oncogene homolog (KRAS) is the most commonly mutated oncogene in human cancer. The developments of many cancers depend on sustained expression and signaling of KRAS, which makes KRAS a high-priority therapeutic target. |
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Please read the User Guide of Recombinant Proteins for more specific information.
HLA-A*11:01&B2M&KRAS WT (VVVGAGGVGK) Tetramer Protein, Human, MHC (His & Avi), PE-Labeled RASK2 KRAS2 KRAS1 MHC C-K-RAS KI-RAS K-RAS4B RALD K-RAS4A NS3 KRAS NS GTPase Kras K-Ras 2 K-RAS2A CFC2 K-RAS2B recombinant recombinant-proteins proteins protein