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NPS ALX Compound 4a hydrochloride(1:1)

🥰Excellent
Catalog No. T12262L1

NPS ALX Compound 4a hydrochloride(1:1) is a potent and selective 5-hydroxytryptamine6 (5-HT6) receptor antagonist, with an IC50 of 7.2 nM and a Ki of 0.2 nM.

NPS ALX Compound 4a hydrochloride(1:1)
Other Forms of NPS ALX Compound 4a hydrochloride(1:1):

NPS ALX Compound 4a hydrochloride(1:1)

🥰Excellent
Purity: 99.84%
Catalog No. T12262L1
NPS ALX Compound 4a hydrochloride(1:1) is a potent and selective 5-hydroxytryptamine6 (5-HT6) receptor antagonist, with an IC50 of 7.2 nM and a Ki of 0.2 nM.
Pack SizePriceAvailabilityQuantity
1 mg$34In Stock
5 mg$81In Stock
10 mg$122In Stock
25 mg$209In Stock
50 mg$303In Stock
100 mg$413In Stock
200 mg$548In Stock
1 mL x 10 mM (in DMSO)$98In Stock
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This molecule is a custom-made product. TargetMol has an excellent synthesis team with the experience and capability to provide you with cost-effective products. However, due to objective factors, there is a small probability that the synthesis may not be successful during the R&D process. We appreciate your understanding. If you have any questions, please feel free to contact us. We are committed to serving you wholeheartedly.
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Batch Information

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Purity:99.84%
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COA LCMS HNMR

Product Introduction

Bioactivity
Description
NPS ALX Compound 4a hydrochloride(1:1) is a potent and selective 5-hydroxytryptamine6 (5-HT6) receptor antagonist, with an IC50 of 7.2 nM and a Ki of 0.2 nM.
Chemical Properties
Molecular Weight468.01
FormulaC25H26ClN3O2S
SmilesO=S(C1=CC=CC2=C1C=CC=C2)(N3C=CC4=C3C=C(N5CCN6CCCC6C5)C=C4)=O.Cl
Relative Density.no data available
ColorYellow
AppearanceSolid
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 55 mg/mL (117.52 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM2.1367 mL10.6835 mL21.3671 mL106.8353 mL
5 mM0.4273 mL2.1367 mL4.2734 mL21.3671 mL
10 mM0.2137 mL1.0684 mL2.1367 mL10.6835 mL
20 mM0.1068 mL0.5342 mL1.0684 mL5.3418 mL
50 mM0.0427 mL0.2137 mL0.4273 mL2.1367 mL
100 mM0.0214 mL0.1068 mL0.2137 mL1.0684 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.
1 Enter information below:
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2 Enter the in vivo formulation:
% DMSO
%
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Dose Conversion

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

NPSALXCompound4ahydrochloride(299433106Freebase)NPS ALX Compound 4a hydrochloride(1:1)5HTReceptor5-HT65HT Receptor
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