Shopping Cart

Your shopping cart is currently empty

Hydroxyprogesterone caproate

Name: Hydroxyprogesterone caproate
Brand: TargetMol
SKU: T6858
Price: 45 USD
Availability: InStock
Rating: 5 (10 reviews)

Copy Product Info

😃Good

Catalog No. T6858Cas No. 630-56-8

Alias Primolut Depot, Hormofort, Delalutin, 17α-Hydroxyprogesterone hexanoate, 17α-Hydroxyprogesterone caproate

Hydroxyprogesterone caproate (Delalutin) is a synthetic progestational agent. It binds to and activates nuclear progesterone receptors in the reproductive system and inhibits ovulation and an alteration in the cervical mucus and endometrium.

Hydroxyprogesterone caproate

Copy Product Info

😃Good

Purity: 99.70%

Catalog No. T6858Alias Primolut Depot, Hormofort, Delalutin, 17α-Hydroxyprogesterone hexanoate, 17α-Hydroxyprogesterone caproateCas No. 630-56-8

Pack Size	Price	USA Warehouse	Global Warehouse
500 mg	$45	-	In Stock
1 g	$53	-	In Stock
1 mL x 10 mM (in DMSO)	$48	In Stock	In Stock

Add to Cart

Add to Quotation

In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

Questions

Batch Information

Select Batch

Purity:99.70%

Appearance:Solid

Color:White

Resource Download

COA LCMS HPLC HNMR

Product Introduction

Bioactivity

Description	Hydroxyprogesterone caproate (Delalutin) is a synthetic progestational agent. It binds to and activates nuclear progesterone receptors in the reproductive system and inhibits ovulation and an alteration in the cervical mucus and endometrium.
In vivo	Hydroxyprogesterone caproate is administered to pregnant rats in order to assess the effect of intraperitoneal exposure to supranormal levels of hydroxyprogesterone caproate on the male reproductive potential in the first generation. The cauda epididymal sperm count and motility decrease significantly in rats exposed to hydroxyprogesterone caproate during embryonic development, when compared with control rats. The levels of serum testosterone decrease with an increase in follicle stimulating hormone and luteinizing hormone in adult rats exposed to hydroxyprogesterone caproate during the embryonic stage[2].
Synonyms	Primolut Depot, Hormofort, Delalutin, 17α-Hydroxyprogesterone hexanoate, 17α-Hydroxyprogesterone caproate

Chemical Properties

Molecular Weight	428.60
Formula	C₂₇H₄₀O₄
Cas No.	630-56-8
Smiles	CCCCCC(=O)O[C@@]1(CC[C@H]2[C@@H]3CCC4=CC(=O)CC[C@]4(C)[C@H]3CC[C@]12C)C(C)=O
Relative Density.	1.0148 g/cm3 (Estimated)

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

H2O: < 1 mg/mL (insoluble or slightly soluble)

DMSO: 50 mg/mL (116.66 mM), Sonication is recommended.

Ethanol: 79 mg/mL (184.32 mM), Sonication is recommended.

In Vivo Formulation

10% DMSO+40% PEG300+5% Tween 80+45% Saline: 2 mg/mL (4.67 mM), Sonication is recommended.

Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.

Solution Preparation Table

DMSO/Ethanol

	1mg	5mg	10mg	50mg
1 mM	2.3332 mL	11.6659 mL	23.3318 mL	116.6589 mL
5 mM	0.4666 mL	2.3332 mL	4.6664 mL	23.3318 mL
10 mM	0.2333 mL	1.1666 mL	2.3332 mL	11.6659 mL
20 mM	0.1167 mL	0.5833 mL	1.1666 mL	5.8329 mL
50 mM	0.0467 mL	0.2333 mL	0.4666 mL	2.3332 mL
100 mM	0.0233 mL	0.1167 mL	0.2333 mL	1.1666 mL

Calculator

Molarity Calculator
Dilution Calculator
Reconstitution Calculator
Molecular Weight Calculator

In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc