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Mal-PEG4-NHS ester

Name: Mal-PEG4-NHS ester
Brand: TargetMol
SKU: T15991
Price: 36 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T15991Cas No. 1325208-25-0

Mal-PEG4-NHS ester is a noncleavable ADC linker with a Maleimide group, a 4-unit PEG, and an NHS ester.

Mal-PEG4-NHS ester

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Purity: 98.31%

Catalog No. T15991Cas No. 1325208-25-0

Mal-PEG4-NHS ester is a noncleavable ADC linker with a Maleimide group, a 4-unit PEG, and an NHS ester.

Pack Size	Price	USA Warehouse	Global Warehouse
5 mg	$36	-	In Stock
10 mg	$52	-	In Stock
25 mg	$83	-	In Stock
50 mg	$123	-	In Stock
100 mg	$189	-	In Stock
500 mg	$423	7-10 days	7-10 days

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

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Batch Information

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Purity:98.31%

Resource Download

COA LCMS HNMR

Product Introduction

Bioactivity

Description

Mal-PEG4-NHS ester is a noncleavable ADC linker with a Maleimide group, a 4-unit PEG, and an NHS ester.

Chemical Properties

Molecular Weight	442.42
Formula	C₁₉H₂₆N₂O₁₀
Cas No.	1325208-25-0
Smiles	O=C(ON1C(=O)CCC1=O)CCOCCOCCOCCOCCN2C(=O)C=CC2=O
Relative Density.	1.36 g/cm3 (Predicted)

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 80 mg/mL (180.82 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	2.2603 mL	11.3015 mL	22.6030 mL	113.0148 mL
5 mM	0.4521 mL	2.2603 mL	4.5206 mL	22.6030 mL
10 mM	0.2260 mL	1.1301 mL	2.2603 mL	11.3015 mL
20 mM	0.1130 mL	0.5651 mL	1.1301 mL	5.6507 mL
50 mM	0.0452 mL	0.2260 mL	0.4521 mL	2.2603 mL
100 mM	0.0226 mL	0.1130 mL	0.2260 mL	1.1301 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc