DcR3 Protein, Human, Recombinant (His)

Name: DcR3 Protein, Human, Recombinant (His)
Brand: TargetMol
SKU: TMPY-07006
Price: 85 USD
Availability: InStock
Rating: 5 (10 reviews)

(Synonyms: UNQ186/PRO212, TR6, M68E, M68, DJ583P15.1.1, DCR3) Copy Product Info

Synonyms: UNQ186/PRO212, TR6, M68E, M68, DJ583P15.1.1, DCR3

Catalog No. TMPY-07006 Copy Product Info

DcR3 Protein, Human, Recombinant (His) is expressed in Baculovirus-Insect Cells. The accession number is O95407.

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Pack Size	Price	USA Stock	Global Stock
5 µg	$85	-	In Stock
10 µg	$138	-	In Stock
20 µg	$233	-	In Stock
50 µg	$460	7-10 days	7-10 days
100 µg	$893	7-10 days	7-10 days
200 µg	$1,320	7-10 days	7-10 days
500 µg	$2,580	7-10 days	7-10 days
1 mg	$5,280	7-10 days	7-10 days

For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)

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For research use only—not for human use. No sales to individuals. Use as intended only.

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Purity:≥ 95% as determined by SDS-PAGE. ≥ 90% as determined by SEC-HPLC.

Appearance:Lyophilized powder

Color:White

Resource Download

COA User Guide of Recombinant Proteins

Product Introduction

Bioactivity

Bioactivity	Immobilized DcR3 Protein, Human, Recombinant (His) (Cat#TMPY-07006) at 2 μg/mL (100 μL/well) can bind TL1A Protein, Human, Recombinant (hFc) (Cat#TMPY-04645), the EC50 is 10-30 ng/mL.
Description	DcR3 Protein, Human, Recombinant (His) is expressed in Baculovirus-Insect Cells. The accession number is O95407.
Species	Human
Expression System	Baculovirus Insect Cells
Tag	C-His
Accession Number	O95407
Construction	A DNA sequence encoding the Human TNFRSF6B (O95407) (Met1-Ser195) was expressed with a polyhistidine tag at the C-terminus.
Protein Purity	≥ 95% as determined by SDS-PAGE. ≥ 90% as determined by SEC-HPLC.
Endotoxin	< 1.0 EU/μg of the protein as determined by the LAL method.
Formulation	Lyophilized from sterile 20 mM PB,300 mM NaCl, 10% Glycerol, pH 7.0. Please contact us for any concerns or special requirements. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Reconstitution	Please refer to the lot-specific COA.
Synonyms	UNQ186/PRO212, TR6, M68E, M68, DJ583P15.1.1, DCR3
Research Background	Tumor necrosis factor receptor superfamily member 6B (TNFRSF6B) also known as DcR3(Decoy Receptor 3) and M68 is the tumor necrosis factor receptor superfamily. DcR3/TNFRSF6B belongs to the tumor necrosis factor receptor superfamily. The encoded protein is postulated to play a regulatory role in suppressing FasL- and LIGHT-mediated cell death. It acts as a decoy receptor that competes with death receptors for ligand binding. Over-expression of this gene has been noted in gastrointestinal tract tumors. Read-through transcription into this gene from the neighboring upstream gene, which encodes regulator of telomere elongation helicase 1 (RTEL1), generates a non-coding transcript. DcR3/TNFRSF6B is detected in fetal lung, brain and liver. DcR3/TNFRSF6B is also detected in adult stomach, spinal cord, lymph node, trachea, spleen, colon and lung. This protein is highly expressed in several primary tumors from colon, stomach, rectum, esophagus and in SW480 colon carcinoma cells.

Chemical Properties

Molecular Weight

19.74 kDa (predicted); 24.5 kDa (reducing contition)

Storage & Solubility Information

Shipping	In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice.
Storage	It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.