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Synonyms: Proliferation marker protein Ki-67, MKI67, Antigen identified by monoclonal antibody Ki-67 (Antigen KI-67;Antigen Ki67)
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 50 μL | $220 | 7-10 days | 7-10 days | |
| 100 μL | $373 | 7-10 days | 7-10 days | |
| 200 μL | $527 | 7-10 days | 7-10 days |
| Description | Anti-MKI67 Polyclonal Antibody 2 is a Rabbit antibody targeting MKI67. Anti-MKI67 Polyclonal Antibody 2 can be used in FCM, ICC/IF. |
| Synonyms | Proliferation marker protein Ki-67, MKI67, Antigen identified by monoclonal antibody Ki-67 (Antigen KI-67;Antigen Ki67) |
| Ig Type | IgG |
| Reactivity | Human |
| Application | |
| Recommended Dose | FCM=1:50-100; ICC/IF=1:100-500 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Nucleus. Chromosome. Predominantly localized in the G1 phase in the perinucleolar region, in the later phases it is also detected throughout the nuclear interior, being predominantly localized in the nuclear matrix. In mitosis, it is present on all chromosomes. |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1 mg/mL |
| Research Background | Ki67 antigen is the prototypic cell cycle related nuclear protein, expressed by proliferating cells in all phases of the active cell cycle (G1, S, G2 and M phase). It is absent in resting (G0) cells. Ki67 antibodies are useful in establishing the cell growing fraction in neoplasms (immunohistochemically quantified by determining the number of Ki67 positive cells among the total number of resting cells = Ki67 index). In neoplastic tissues the prognostic value is comparable to the tritiated thymidine labelling index. The correlation between low Ki67 index and histologically low grade tumours is strong. Ki67 is routinely used as a neuronal marker of cell cycling and proliferation. |
| Immunogen | KLH conjugated synthetic peptide: human Ki-67 |
| Antigen Species | Human |
| Gene Name | MKI67 |
| Gene ID | |
| Protein Name | Proliferation marker protein Ki-67 |
| Uniprot ID | |
| Biology Area | Cell division,Tumor biomarkers,Markers,Soma marker,Neurogenesis,Replication |
| Function | Thought to be required for maintaining cell proliferation. |
| Molecular Weight | Theoretical: 358 kDa. |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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