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CD27/TNFRSF7 Protein, Human, Recombinant (hFc & His)
(Synonyms: Tumor necrosis factor receptor superfamily member 7, T-cell activation antigen CD27, T14 and TNFRSF7., CD27L receptor, CD27 antigen) Copy Product InfoSynonyms: Tumor necrosis factor receptor superfamily member 7, T-cell activation antigen CD27, T14 and TNFRSF7., CD27L receptor, CD27 antigen
Catalog No. TMPJ-00421 Copy Product Info
CD27 antigen is also known as CD27L receptor, T-cell activation antigen CD27, Tumor necrosis factor receptor superfamily member 7, T14 and TNFRSF7. In humans, it is encoded by the CD27 gene. CD27 is a single-pass type I membrane protein with 3 TNFR-Cys repeats. It is a member of the TNF-receptor superfamily and is required for generation and long-term maintenance of T cell immunity. It binds to ligand CD70, and plays a key role in regulating B-cell activation and immunoglobulin synthesis. It plays a role in survival of activated T-cells and apoptosis through association with SIVA1.
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 5 μg | $32 | 7-10 days | 7-10 days | |
| 10 μg | $47 | 7-10 days | 7-10 days | |
| 20 μg | $75 | 7-10 days | 7-10 days | |
| 50 μg | $148 | 7-10 days | 7-10 days | |
| 100 μg | $256 | 7-10 days | 7-10 days | |
| 200 μg | $449 | 7-10 days | 7-10 days | |
| 500 μg | $955 | 7-10 days | 7-10 days | |
| 1 mg | $1,370 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction
Bioactivity
Chemical Properties
Storage & Solubility Information
| Description | CD27 antigen is also known as CD27L receptor, T-cell activation antigen CD27, Tumor necrosis factor receptor superfamily member 7, T14 and TNFRSF7. In humans, it is encoded by the CD27 gene. CD27 is a single-pass type I membrane protein with 3 TNFR-Cys repeats. It is a member of the TNF-receptor superfamily and is required for generation and long-term maintenance of T cell immunity. It binds to ligand CD70, and plays a key role in regulating B-cell activation and immunoglobulin synthesis. It plays a role in survival of activated T-cells and apoptosis through association with SIVA1. |
| Species | Human |
| Expression System | HEK293 Cells |
| Tag | C-hFc-6xHis |
| Accession Number | P26842 |
| Amino Acid | Thr21-Ile192 |
| Construction | Thr21-Ile192 |
| Protein Purity | Greater than 95% as determined by reducing SDS-PAGE. (QC verified) |
| Endotoxin | < 0.1 ng/µg (1 EU/µg) as determined by LAL test. |
| Formulation | Lyophilized from a solution filtered through a 0.22 μm filter, containing 20 mM Tris-HCl, 150 mM NaCl, pH 8.0. |
| Reconstitution | Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing. |
| Stability & Storage | Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots. |
| Shipping | In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice. |
| Synonyms | Tumor necrosis factor receptor superfamily member 7, T-cell activation antigen CD27, T14 and TNFRSF7., CD27L receptor, CD27 antigen |
| Research Background |
| Molecular Weight | 60 KDa (reducing condition) |
| Storage | Lyophilized powder: -20~-80°C for 1 year | Solution: -80°C for 6 months |
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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Related Tags: CD27/TNFRSF7 Protein, Human, Recombinant (hFc & His) chemical structure | CD27/TNFRSF7 Protein, Human, Recombinant (hFc & His) molecular weight
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