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CD27/TNFRSF7 Protein, Human, Recombinant (hFc & His)

(Synonyms: Tumor necrosis factor receptor superfamily member 7, T-cell activation antigen CD27, T14 and TNFRSF7., CD27L receptor, CD27 antigen) Copy Product Info

Synonyms: Tumor necrosis factor receptor superfamily member 7, T-cell activation antigen CD27, T14 and TNFRSF7., CD27L receptor, CD27 antigen

Catalog No. TMPJ-00421 Copy Product Info
CD27 antigen is also known as CD27L receptor, T-cell activation antigen CD27, Tumor necrosis factor receptor superfamily member 7, T14 and TNFRSF7. In humans, it is encoded by the CD27 gene. CD27 is a single-pass type I membrane protein with 3 TNFR-Cys repeats. It is a member of the TNF-receptor superfamily and is required for generation and long-term maintenance of T cell immunity. It binds to ligand CD70, and plays a key role in regulating B-cell activation and immunoglobulin synthesis. It plays a role in survival of activated T-cells and apoptosis through association with SIVA1.
Pack SizePriceUSA StockGlobal StockQuantity
5 µg$327-10 days7-10 days
10 µg$477-10 days7-10 days
20 µg$757-10 days7-10 days
50 µg$1487-10 days7-10 days
100 µg$2567-10 days7-10 days
200 µg$4497-10 days7-10 days
500 µg$9557-10 days7-10 days
1 mg$1,3707-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Bioactivity
Activity has not been tested. It is theoretically active, but we cannot guarantee it. If you require protein activity, we recommend choosing the eukaryotic expression version first.
Description
CD27 antigen is also known as CD27L receptor, T-cell activation antigen CD27, Tumor necrosis factor receptor superfamily member 7, T14 and TNFRSF7. In humans, it is encoded by the CD27 gene. CD27 is a single-pass type I membrane protein with 3 TNFR-Cys repeats. It is a member of the TNF-receptor superfamily and is required for generation and long-term maintenance of T cell immunity. It binds to ligand CD70, and plays a key role in regulating B-cell activation and immunoglobulin synthesis. It plays a role in survival of activated T-cells and apoptosis through association with SIVA1.
Species
Human
Expression System
HEK293 Cells
TagC-hFc-6xHis
Accession NumberP26842
Amino AcidThr21-Ile192
ConstructionThr21-Ile192
Protein Purity
Greater than 95% as determined by reducing SDS-PAGE. (QC verified)
Endotoxin< 0.1 ng/µg (1 EU/µg) as determined by LAL test.
FormulationLyophilized from a solution filtered through a 0.22 μm filter, containing 20 mM Tris-HCl, 150 mM NaCl, pH 8.0.
ReconstitutionReconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
SynonymsTumor necrosis factor receptor superfamily member 7, T-cell activation antigen CD27, T14 and TNFRSF7., CD27L receptor, CD27 antigen
Research Background
CD27 antigen is also known as CD27L receptor, T-cell activation antigen CD27, Tumor necrosis factor receptor superfamily member 7, T14 and TNFRSF7. In humans, it is encoded by the CD27 gene. CD27 is a single-pass type I membrane protein with 3 TNFR-Cys repeats. It is a member of the TNF-receptor superfamily and is required for generation and long-term maintenance of T cell immunity. It binds to ligand CD70, and plays a key role in regulating B-cell activation and immunoglobulin synthesis. It plays a role in survival of activated T-cells and apoptosis through association with SIVA1.
Chemical Properties
Molecular Weight60 KDa (reducing condition)
Storage & Solubility Information
ShippingIn general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice.
StorageLyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.

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Related Tags: CD27/TNFRSF7 Protein, Human, Recombinant (hFc & His) chemical structure | CD27/TNFRSF7 Protein, Human, Recombinant (hFc & His) molecular weight