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Anti-CA9/Carbonic Anhydrase IX Antibody-PE (4F130)

🥰Excellent
Catalog No. TMAY-00272P

Anti-CA9/Carbonic Anhydrase IX Antibody-PE (4F130) is a PE-conjugated Rabbit antibody targeting CA9/Carbonic Anhydrase IX. Anti-CA9/Carbonic Anhydrase IX Antibody-PE (4F130) can be used in FCM.

Anti-CA9/Carbonic Anhydrase IX Antibody-PE (4F130)

Anti-CA9/Carbonic Anhydrase IX Antibody-PE (4F130)

🥰Excellent
Catalog No. TMAY-00272P
Anti-CA9/Carbonic Anhydrase IX Antibody-PE (4F130) is a PE-conjugated Rabbit antibody targeting CA9/Carbonic Anhydrase IX. Anti-CA9/Carbonic Anhydrase IX Antibody-PE (4F130) can be used in FCM.
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Product Introduction

Bioactivity
Description
Anti-CA9/Carbonic Anhydrase IX Antibody-PE (4F130) is a PE-conjugated Rabbit antibody targeting CA9/Carbonic Anhydrase IX. Anti-CA9/Carbonic Anhydrase IX Antibody-PE (4F130) can be used in FCM.
Ig Type
Monoclonal Rabbit IgG
Clone
4F130
Reactivity
Human
Verified Activity
Flow cytometric analysis of Human CAIX expression on Hela cells. Cells were stained with PE-conjugated anti-Human CAIX. The fluorescence histograms were derived from gated events with the forward and side light-scatter characteristics of intact cells.
Application
FCM
Recommended Dose
5 μl/Test, 0.1 mg/ml
Antibody Type
Monoclonal
Host SpeciesRabbit
ConstructionThis antibody was obtained from a rabbit immunized with purified, recombinant Human Carbonic Anhydrase IX/CA9 (rh Carbonic Anhydrase IX/CA9; TMPY-00690; NP_001207.2; Met1-Asp414) and conjugated with PE under optimum conditions, the unreacted PE was removed.
PurificationProtein A
AppearanceLiquid
FormulationPBS solution containing 0.5% BSA and 0.03%ProClin300
Research BackgroundCarbonic anhydrases IX (CA IX), also known as membrane antigen MN or CA9, is a member of the carbonic anhydrase (CA) family and may be involved in cell proliferation and cellular transformation. CAs are zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide (H2O + CO2 = H+ + HCO3–) and thus participate in a variety of biological and physical processes. CA IX protein is expressed primarily in carcinoma cells lines, and the expression is cell density dependent and has been shown to be strongly induced by hypoxia, accordingly facilitates adaptation of tumor cells to hypoxic conditions. It is involved in tumorigenesis through many pathways, such as pH regulation and cell adhesion control. CA IX is used as a marker of tumor hypoxia and as a new therapeutic target for many human carcinomas and cancers.Cancer ImmunotherapyImmune CheckpointImmunotherapyTargeted Therapy
Related Conjugates and Formulations
Conjucates
PE
Others Formats
Unconjugated/FITC
Antibody Types Available
3
Antigen Details
Immunogen
Recombinant Human Carbonic Anhydrase IX/CA9 Protein (TMPY-00690)
Antigen Species
Human
Biology Area
Cancer Drug Targets
Chemical Properties
Stability & Storage
Stability & StorageStore at 2°C-8°C for 12 months, do not freeze. Keep away from direct sunlight.
TransportShipping with blue ice.

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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