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Anti-GPA33/A33 Antibody (8S10)
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Catalog No. TMAY-01818
Alias MGC129987, MGC129986, GPA33, Glycoprotein A33, A33
Anti-GPA33/A33 Antibody (8S10) is a Rabbit antibody targeting GPA33/A33. Anti-GPA33/A33 Antibody (8S10) can be used in ELISA.
Anti-GPA33/A33 Antibody (8S10)
Anti-GPA33/A33 Antibody (8S10)
😃Good
Catalog No. TMAY-01818Alias MGC129987, MGC129986, GPA33, Glycoprotein A33, A33
Anti-GPA33/A33 Antibody (8S10) is a Rabbit antibody targeting GPA33/A33. Anti-GPA33/A33 Antibody (8S10) can be used in ELISA.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 100 μL | $269 | 7-10 days |
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Antigen Details
Chemical Properties
| Description | Anti-GPA33/A33 Antibody (8S10) is a Rabbit antibody targeting GPA33/A33. Anti-GPA33/A33 Antibody (8S10) can be used in ELISA. |
| Alias | MGC129987, MGC129986, GPA33, Glycoprotein A33, A33 |
| Ig Type | Monoclonal Rabbit IgG |
| Clone | 8S10 |
| Reactivity | Human |
| Application | ELISA |
| Recommended Dose | ELISA: 1:5000-1:10000 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Construction | This antibody was obtained from a rabbit immunized with purified, recombinant Human GPA33 (rh GPA33; TMPY-02012; Q99795-1; Met1-Val235). |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | 0.2 μm filtered solution in PBS |
| Research Background | Cell surface A33 antigen, also known as glycoprotein A33, is a single-pass type I membrane protein that is expressed in the normal gastrointestinal epithelium and 95% of colon cancers. GPA33 contains one Ig-like C2-type (immunoglobulin-like) domain and one Ig-like V-type (immunoglobulin-like) domain. The open reading frame encodes a 319-amino acid polypeptide having a putative secretory signal sequence and 3 potential glycosylation sites. The predicted mature protein has a 213-amino acid extracellular region, a single transmembrane domain, and a 62-amino acid intracellular tail. Intracellular traffic and recycling to the cell surface appear to play a major role in GPA33 function and to have an influence on its surface density superseding translational regulation. GPA33 has become a promising target of immunologic therapy strategies, but its biologic function and potential role in tumorigenesis are unknown. EpCAM protein and GPA33 mRNA expressions are specific and sensitive markers of Barrett's metaplasia (BM). GPA33 may also play a role in cell-cell recognition and signaling.Cancer ImmunotherapyImmune CheckpointImmunotherapyTargeted Therapy |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Human GPA33 protein (TMPY-02012) |
| Antigen Species | Human |
| Biology Area | Cancer Drug Targets |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| Transport | Shipping with blue ice. |
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