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Eprociclovir
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Catalog No. T31659Cas No. 145512-85-2
Alias AV-10, AV10, AV 10, A-5021, A5021, A 5021
Eprociclovir (A-5021) is a novel acyclovir analog that is a potent inhibitor of EHV1 replication and may be used for the treatment and/or prevention of infections with this virus.Eprociclovir has potent anti-herpetic activity against most human herpesviruses.
Eprociclovir
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Purity: 99.86%
Catalog No. T31659Alias AV-10, AV10, AV 10, A-5021, A5021, A 5021Cas No. 145512-85-2
Eprociclovir (A-5021) is a novel acyclovir analog that is a potent inhibitor of EHV1 replication and may be used for the treatment and/or prevention of infections with this virus.Eprociclovir has potent anti-herpetic activity against most human herpesviruses.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 1 mg | $160 | In Stock | In Stock | |
| 5 mg | $400 | In Stock | In Stock | |
| 25 mg | $985 | In Stock | In Stock | |
| 50 mg | $1,280 | In Stock | In Stock |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
This molecule is a custom-made product. TargetMol has an excellent synthesis team with the experience and capability to provide you with cost-effective products.If you have any questions, please feel free to contact us. We are committed to serving you wholeheartedly.
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.
Batch Information
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Purity:99.86%
ee:100%
Appearance:Solid
Color:White
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Product Introduction
Eprociclovir AI Summary
Eprociclovir exhibits potent antiviral bioactivity against various herpes viruses. It demonstrates strong inhibitory activity against Herpes simplex virus type-1 (HSV-1) with an IC50 value of 0.02 ug/mL and against Varicella zoster virus (VZV), showing IC50 values ranging from 0.2 to 0.67 ug/mL. The compound also exhibits effective inhibition against multiple strains of HSV-1 and HSV-2 in cell lines, with IC50 values between 0.0093 and 0.12 ug/mL. Furthermore, Eprociclovir has a high selectivity index of 1600.0, indicating a favorable ratio of antiviral activity to cytotoxicity. It presents high cytotoxic concentration thresholds, with CC50 values of 240.0 ug/mL for vero cells and a maximum tolerated concentration (MTC) of 320.0 ug/mL for HFF cells. However, it shows limited inhibitory activity against the HIV-1 strain, with an IC50 value exceeding 100.0 ug/mL..
Note: Summary generated by AI. Data source: ChEMBL 
Bioactivity
Chemical Properties
Storage & Solubility Information
| Description | Eprociclovir (A-5021) is a novel acyclovir analog that is a potent inhibitor of EHV1 replication and may be used for the treatment and/or prevention of infections with this virus.Eprociclovir has potent anti-herpetic activity against most human herpesviruses. |
| Synonyms | AV-10, AV10, AV 10, A-5021, A5021, A 5021 |
| Molecular Weight | 265.27 |
| Formula | C11H15N5O3 |
| Cas No. | 145512-85-2 |
| Smiles | C([C@@]1(CO)[C@H](CO)C1)N2C3=C(N=C2)C(=O)N=C(N)N3 |
| Relative Density. | no data available |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
Calculator
In Vivo Formulation Calculator (Clear solution)
Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:
For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, and a total of 10 animals are to be administered, using a formulation of 
10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH2O , the resulting working solution concentration would be 2 mg/mL.Stock Solution Preparation:
Dissolve 2 mg of the compound in 100 μL DMSO to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.
Preparation of the In Vivo Formulation:
1) Add 100 μL of the DMSO stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.
2) Add 50 μL Tween 80 and mix well until fully clarified.
3) Add 450 μL Saline,PBS or ddH2O and mix thoroughly until a homogeneous solution is obtained.
This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.
Dose Conversion
You can also refer to dose conversion for different animals. More Dose Conversion
Tech Support
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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