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IGFBP-2 Protein, Human, Recombinant (aa 40-325. His) is expressed in HEK293 Cells. The accession number is P18065.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
10 μg | $113 | 7-10 days | |
50 μg | $497 | 7-10 days | |
1 mg | $4,290 | 7-10 days |
Biological Activity | ED 50 < 2.0 μg/ml, measured in a bioassay using FDC-P1 cells in the presence of 15.0 ng/ml human IGF-II. |
Description | IGFBP-2 Protein, Human, Recombinant (aa 40-325. His) is expressed in HEK293 Cells. The accession number is P18065. |
Species | Human |
Expression System | HEK293 Cells |
Tag | His |
Accession Number | P18065 |
Synonyms | Insulin-like growth factor-binding protein 2,IBP-2,BP-2 |
Construction | Phe40-Gln325 |
Protein Purity | > 95% as determined by SDS-PAGE |
Molecular Weight | 6~20 kDa (Reducing conditions) |
Endotoxin | < 0.2 EU/μg of protein as determined by the LAL method. |
Formulation | Lyophilized from a 0.2 μm filtered solution in PBS. |
Reconstitution | Reconstitute the lyophilized protein in sterile deionized water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing. |
Stability & Storage | Upon receiving, this product remains stable for up to 6 months at lower than -70°C. Upon reconstitution, the product should be stable for up to 1 week at 4°C or up to 3 months at -20°C. For long term storage it is recommended that a carrier protein (example 0.1% BSA) be added. Avoid repeated freeze-thaw cycles. |
Shipping | In general, Lyophilized powders are shipping with blue ice. Solutions are shipping with dry ice. |
Research Background | IGF-BP-2, also known as Insulin-like growth factor-binding protein 2, IBP-2 and BP-2, is a cysteine-rich secreted protein belonging to the IGF-binding protein superfamily. It is expressed by the central nervous system, bone cells and reproductive tissues. IGF-BP-2 binds to both IGF-I and IGF-II, with a much higher binding affinity to IGF-II than IGF-I. IGF-BP-2 has been shown to inhibitand stimulate the growth promoting effects of IGFs, thus serving as a regulator for IGF distribution, function and activity. |
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