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Anti-SLAMF6 Antibody (3Z84)

😃Good
Catalog No. TMAY-02160
Alias SLAM family member 6, SF2000, NTB-A, NTBA, Ly108, KALIb, KALI, CD352

Anti-SLAMF6 Antibody (3Z84) is a Rabbit antibody targeting SLAMF6. Anti-SLAMF6 Antibody (3Z84) can be used in IHC-P.

Anti-SLAMF6 Antibody (3Z84)

Anti-SLAMF6 Antibody (3Z84)

😃Good
Catalog No. TMAY-02160Alias SLAM family member 6, SF2000, NTB-A, NTBA, Ly108, KALIb, KALI, CD352
Anti-SLAMF6 Antibody (3Z84) is a Rabbit antibody targeting SLAMF6. Anti-SLAMF6 Antibody (3Z84) can be used in IHC-P.
Pack SizePriceAvailabilityQuantity
20 μL$93 7-10 days
100 μL$269 7-10 days
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Product Introduction

Bioactivity
Description
Anti-SLAMF6 Antibody (3Z84) is a Rabbit antibody targeting SLAMF6. Anti-SLAMF6 Antibody (3Z84) can be used in IHC-P.
AliasSLAM family member 6, SF2000, NTB-A, NTBA, Ly108, KALIb, KALI, CD352
Ig Type
Monoclonal Rabbit IgG
Clone
3Z84
Reactivity
Human
Verified Activity
1. Immunochemical staining of human SLAMF6 in human tonsil with rabbit monoclonal antibody (1:200, formalin-fixed paraffin embedded sections).

2. Immunochemical staining of human SLAMF6 in human spleen with rabbit monoclonal antibody (1:200, formalin-fixed paraffin embedded sections).

3. Immunochemical staining of human SLAMF6 in human appendix with rabbit monoclonal antibody (1:200, formalin-fixed paraffin embedded sections).
Application
IHC-P
Recommended Dose
IHC-P: 1:100-1:500
Antibody Type
Monoclonal
Host SpeciesRabbit
ConstructionThis antibody was obtained from a rabbit immunized with purified, recombinant Human Ly108 / SLAMF6 (rh Ly108 / SLAMF6; TMPY-01914; Q96DU3-1; Met1-Met226).
PurificationProtein A
AppearanceLiquid
Formulation0.2 μm filtered solution in PBS
Research BackgroundSLAM family member 6, also known as Activating NK receptor, NK-T-B-antigen, NTB-A, SLAMF6, KALI and Ly18, is a single-pass type I membrane protein that belongs to the CD2 subfamily of the immunoglobulin superfamily. SLAMF6 / Ly18 contains one Ig-like (immunoglobulin-like) domain. It is expressed by all (resting and activated) natural killer cells (NK), T- and B-lymphocytes. SLAMF6 / Ly18 triggers cytolytic activity only in natural killer cells (NK) expressing high surface densities of natural cytotoxicity receptors. SLAMF6 / Ly18 is a homodimer. It interacts with PTN6 and, upon phosphorylation, with PTN11 and SH2D1A/SAP. SLAMF6 / Ly18 undergoes tyrosine phosphorylation and associates with the Src homology 2 domain-containing protein (SH2D1A) as well as with SH2 domain-containing phosphatases (SHPs). It may function as a coreceptor in the process of NK cell activation. SLAMF6 / Ly18 can also mediate inhibitory signals in NK cells from X-linked lymphoproliferative patients.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
Recombinant Human Ly108 / SLAMF6 protein (TMPY-01914)
Antigen Species
Human
Biology Area
ITIM/ITAM Immunoreceptors and Related Molecules
Chemical Properties
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
TransportShipping with blue ice.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

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