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Anti-SLAMF6 Antibody (3Z84)
😃Good
Catalog No. TMAY-02160
Alias SLAM family member 6, SF2000, NTB-A, NTBA, Ly108, KALIb, KALI, CD352
Anti-SLAMF6 Antibody (3Z84) is a Rabbit antibody targeting SLAMF6. Anti-SLAMF6 Antibody (3Z84) can be used in IHC-P.
Anti-SLAMF6 Antibody (3Z84)
Anti-SLAMF6 Antibody (3Z84)
😃Good
Catalog No. TMAY-02160Alias SLAM family member 6, SF2000, NTB-A, NTBA, Ly108, KALIb, KALI, CD352
Anti-SLAMF6 Antibody (3Z84) is a Rabbit antibody targeting SLAMF6. Anti-SLAMF6 Antibody (3Z84) can be used in IHC-P.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 20 μL | $93 | 7-10 days | |
| 100 μL | $269 | 7-10 days |
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
| Description | Antibody Type: Rabbit Monoclonal Application: IHC-P Reactivity: Human |
| Alias | SLAM family member 6, SF2000, NTB-A, NTBA, Ly108, KALIb, KALI, CD352 |
| Ig Type | Rabbit IgG |
| Clone | 3Z84 |
| Reactivity | Human |
| Verified Activity | 1. Immunochemical staining of human SLAMF6 in human tonsil with rabbit monoclonal antibody (1:200, formalin-fixed paraffin embedded sections). 2. Immunochemical staining of human SLAMF6 in human spleen with rabbit monoclonal antibody (1:200, formalin-fixed paraffin embedded sections). 3. Immunochemical staining of human SLAMF6 in human appendix with rabbit monoclonal antibody (1:200, formalin-fixed paraffin embedded sections). |
| Application | IHC-P |
| Recommended Dose | IHC-P: 1:100-1:500 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Construction | This antibody was obtained from a rabbit immunized with purified, recombinant Human Ly108 / SLAMF6 (rh Ly108 / SLAMF6; TMPY-01914; Q96DU3-1; Met1-Met226). |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | 0.2 μm filtered solution in PBS |
| Research Background | SLAM family member 6, also known as Activating NK receptor, NK-T-B-antigen, NTB-A, SLAMF6, KALI and Ly18, is a single-pass type I membrane protein that belongs to the CD2 subfamily of the immunoglobulin superfamily. SLAMF6 / Ly18 contains one Ig-like (immunoglobulin-like) domain. It is expressed by all (resting and activated) natural killer cells (NK), T- and B-lymphocytes. SLAMF6 / Ly18 triggers cytolytic activity only in natural killer cells (NK) expressing high surface densities of natural cytotoxicity receptors. SLAMF6 / Ly18 is a homodimer. It interacts with PTN6 and, upon phosphorylation, with PTN11 and SH2D1A/SAP. SLAMF6 / Ly18 undergoes tyrosine phosphorylation and associates with the Src homology 2 domain-containing protein (SH2D1A) as well as with SH2 domain-containing phosphatases (SHPs). It may function as a coreceptor in the process of NK cell activation. SLAMF6 / Ly18 can also mediate inhibitory signals in NK cells from X-linked lymphoproliferative patients. |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Protein: Human Ly108 / SLAMF6 protein (TMPY-01914) |
| Antigen Species | Human |
| Biology Area | ITIM/ITAM Immunoreceptors and Related Molecules |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| Transport | Shipping with blue ice. |
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