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Anti-SPARC Polyclonal Antibody

(Synonyms: SPARC, secreted protein, acidic, cysteine-rich (osteonectin)) Copy Product Info
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Synonyms: SPARC, secreted protein, acidic, cysteine-rich (osteonectin)

Catalog No. TMAB-01764 Copy Product Info
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Anti-SPARC Polyclonal Antibody is a Rabbit antibody targeting SPARC. Anti-SPARC Polyclonal Antibody can be used in FCM,IF,IHC-Fr,IHC-P,WB.
Anti-SPARC Polyclonal Antibody
Pack SizePriceUSA StockGlobal StockQuantity
50 μL$2227-10 days7-10 days
100 μL$3737-10 days7-10 days
200 μL$5287-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-SPARC Polyclonal Antibody is a Rabbit antibody targeting SPARC. Anti-SPARC Polyclonal Antibody can be used in FCM,IF,IHC-Fr,IHC-P,WB.
SynonymsSPARC, secreted protein, acidic, cysteine-rich (osteonectin)
Ig Type
IgG
Reactivity
Human,Mouse,Rat (predicted:Dog,Pig,Cow,Horse,Rabbit)
Application
Recommended Dose
WB: 1:500-2000; IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500; FCM: 2ug/Test
Antibody Type
Polyclonal
Host SpeciesRabbit
Subcellular LocalizationSecreted, extracellular space, extracellular matrix, basement membrane. Note=In or around the basement membrane.
ConstructionPolyclonal Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Concentration1 mg/mL
Research BackgroundThis gene encodes a cysteine-rich acidic matrix-associated protein. The encoded protein is required for the collagen in bone to become calcified but is also involved in extracellular matrix synthesis and promotion of changes to cell shape. The gene product has been associated with tumor suppression but has also been correlated with metastasis based on changes to cell shape which can promote tumor cell invasion. [provided by RefSeq, Dec 2011].
Antigen Details
Immunogen
KLH conjugated synthetic peptide: human SPARC
Antigen Species
Human
Gene Name
SPARC
Gene ID
Protein Name
SPARC
Uniprot ID
Biology Area
Receptor tyrosine kinases,Extracellular Matrix,Cell Cycle Inhibitors,Endoderm,Bone,Receptor Tyrosine Kinases,Endoderm,Osteogenesis
Function
Appears to regulate cell growth through interactions with the extracellular matrix and cytokines. Binds calcium and copper, several types of collagen, albumin, thrombospondin, PDGF and cell membranes. There are two calcium binding sites; an acidic domain that binds 5 to 8 Ca(2+) with a low affinity and an EF-hand loop that binds a Ca(2+) ion with a high affinity.
Chemical Properties
Molecular WeightTheoretical: 33 kDa. Actual: 33-35 kDa.
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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