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FPR A14

Name: FPR A14
Brand: TargetMol
SKU: T22789
Price: 30 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T22789Cas No. 329691-12-5

FPR A14 is an agonist of formyl peptide receptor (FPR) and induces cell differentiation.

FPR A14

😃Good

Purity: 99.84%

Catalog No. T22789Cas No. 329691-12-5

FPR A14 is an agonist of formyl peptide receptor (FPR) and induces cell differentiation.

Pack Size	Price	USA Warehouse	Global Warehouse
5 mg	$30	In Stock	In Stock
10 mg	$51	In Stock	In Stock
25 mg	$111	In Stock	In Stock
50 mg	$188	In Stock	In Stock
100 mg	$280	In Stock	In Stock
200 mg	$398	-	In Stock
1 mL x 10 mM (in DMSO)	$38	In Stock	In Stock

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

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Purity:99.84%

Appearance:Solid

Color:White

Resource Download

COA LCMS HNMR

Product Introduction

Bioactivity

Description	FPR A14 is an agonist of formyl peptide receptor (FPR) and induces cell differentiation.
Targets&IC50	Ca2+ chemoattractant:42 nM, Ca2+ release:630 nM
In vitro	FPR A14 activates neutrophil Ca2+ release and chemoattractant with EC50s of 630 nM and 42 nM[1]. In mouse neuroblastoma N2a cells, FPR A14 (10 μM) increases cell differentiation by 93.3%[2].

Chemical Properties

Molecular Weight	404.42
Formula	C₂₃H₂₀N₂O₅
Cas No.	329691-12-5
Smiles	COc1cc(\C=N\NC(=O)c2ccc3OCOc3c2)ccc1OCc1ccccc1
Relative Density.	1.26 g/cm3 (Predicted)

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 45 mg/mL (111.27 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	2.4727 mL	12.3634 mL	24.7268 mL	123.6338 mL
5 mM	0.4945 mL	2.4727 mL	4.9454 mL	24.7268 mL
10 mM	0.2473 mL	1.2363 mL	2.4727 mL	12.3634 mL
20 mM	0.1236 mL	0.6182 mL	1.2363 mL	6.1817 mL
50 mM	0.0495 mL	0.2473 mL	0.4945 mL	2.4727 mL
100 mM	0.0247 mL	0.1236 mL	0.2473 mL	1.2363 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc