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Anti-Phospho-AKT1 (Ser129) Polyclonal Antibody (Synonyms: p-AKT1 (Ser129), p-AKT1 (S129), AKT1 (p-Ser129), AK...)

Catalog No. TMAC-00109 Copy Product Info
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Anti-Phospho-AKT1 (Ser129) Polyclonal Antibody is a Rabbit antibody targeting Phospho-AKT1 (Ser129). Anti-Phospho-AKT1 (Ser129) Polyclonal Antibody can be used in WB.

Anti-Phospho-AKT1 (Ser129) Polyclonal Antibody

Copy Product Info
🥰Excellent
Catalog No. TMAC-00109
Synonyms p-AKT1 (Ser129), p-AKT1 (S129), AKT1 (p-Ser129), AKT1 (p-S129)

Anti-Phospho-AKT1 (Ser129) Polyclonal Antibody is a Rabbit antibody targeting Phospho-AKT1 (Ser129). Anti-Phospho-AKT1 (Ser129) Polyclonal Antibody can be used in WB.

Anti-Phospho-AKT1
(Ser129) Polyclonal Antibody
Pack SizePriceUSA StockGlobal StockQuantity
50 μL$2187-10 days7-10 days
100 μL$3177-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-Phospho-AKT1 (Ser129) Polyclonal Antibody is a Rabbit antibody targeting Phospho-AKT1 (Ser129). Anti-Phospho-AKT1 (Ser129) Polyclonal Antibody can be used in WB.
Synonymsp-AKT1 (Ser129), p-AKT1 (S129), AKT1 (p-Ser129), AKT1 (p-S129)
Ig Type
IgG
Reactivity
Human,Mouse,Rat
Verified Activity
1. Western blot analysis of extracts from A549 cells treated with PMA using Phospho-Akt (Ser129) antibody TMAC-00109. The lane on the right is treated with the antigen-specific peptide.
verifiedActivity
Application
Recommended Dose
WB: 1:500-1000
Antibody Type
Polyclonal
Host SpeciesRabbit
ConstructionPolyclonal Antibody
PurificationAntibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.
AppearanceLiquid
FormulationRabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Research BackgroundGeneral protein kinase capable of phosphorylating several known proteins. Phosphorylates TBC1D4. Signals downstream of phosphatidylinositol 3-kinase (PI3K) to mediate the effects of various growth factors such as platelet-derived growth factor (PDGF), epidermal growth factor (EGF), insulin and insulin-like growth factor I (IGF-I). Plays a role in glucose transport by mediating insulin-induced translocation of the GLUT4 glucose transporter to the cell surface. Mediates the antiapoptotic effects of IGF-I. Mediates insulin-stimulated protein synthesis by phosphorylating TSC2 at 'Ser-939' and 'Thr-1462', thereby activating mTORC1 signaling and leading to both phosphorylation of 4E-BP1 and in activation of RPS6KB1. Promotes glycogen synthesis by mediating the insulin-induced activation of glycogen synthase.
Related Conjugates and Formulations
Conjucates
Unconjugated
Others Formats
Phospho
Antigen Details
Immunogen
Peptide sequence around phosphorylation site of serine129(D-N-S(p)-G-A) derived from Human Akt
Antigen Species
human
Uniprot ID
Chemical Properties
Molecular WeightActual: 65 kDa.
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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