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Anti-IL-6R Antibody-PE (5L295) (Alias: interleukin 6 receptor, IL6RQ, IL-6RA, IL6RA, IL-6R-1, IL-6R, IL...)
Catalog No. TMAY-00760P Copy Product Info
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Anti-IL-6R Antibody-PE (5L295) is a PE-conjugated Mouse antibody targeting IL-6R. Anti-IL-6R Antibody-PE (5L295) can be used in FCM.
Anti-IL-6R Antibody-PE (5L295)
Copy Product Info🥰Excellent
Catalog No. TMAY-00760P
Alias interleukin 6 receptor, IL6RQ, IL-6RA, IL6RA, IL-6R-1, IL-6R, IL6Q, gp80, CD126
Anti-IL-6R Antibody-PE (5L295) is a PE-conjugated Mouse antibody targeting IL-6R. Anti-IL-6R Antibody-PE (5L295) can be used in FCM.
Anti-IL-6R Antibody-PE
(5L295)
(5L295)
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 25 T | $105 | 7-10 days | 7-10 days | |
| 100 T | $327 | 7-10 days | 7-10 days |
In stock · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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| Description | Anti-IL-6R Antibody-PE (5L295) is a PE-conjugated Mouse antibody targeting IL-6R. Anti-IL-6R Antibody-PE (5L295) can be used in FCM. |
| Synonyms | interleukin 6 receptor, IL6RQ, IL-6RA, IL6RA, IL-6R-1, IL-6R, IL6Q, gp80, CD126 |
| Ig Type | Mouse IgG1 |
| Clone | 5L295 |
| Reactivity | Human |
| Specificity | Human IL-6R |
| Verified Activity | Flow cytometric analysis of Human IL-6R expression on U266 cells. Cells were stained with PE-conjugated anti-Human IL-6R. The fluorescence histograms were derived from gated events with the forward and side light-scatter characteristics of intact cells. |
| Application | |
| Recommended Dose | 5 μl/Test, 0.1 mg/ml |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human IL6R / CD126 (rh IL6R / CD126; TMPY-00864; NP_000556.1; Met1-Pro365) and conjugated with PE under optimum conditions, the unreacted PE was removed. |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | PBS solution containing 0.5% BSA and 0.03%ProClin300 |
| Research Background | Interleukin 6 receptor (IL-6R) also known as CD126 (Cluster of Differentiation 126) is a type I cytokine receptor. The low concentration of a soluble form of IL-6 receptor (SIL-6R) acts as an agonist of IL-6 activity. In the IL-6R/CD126/IL6R system, both a membrane-bound IL-6R and a SIL-6R protein can mediate IL-6 signals into the cells through the interaction of gp130. The resulting IL-6/sIL-6R protein complex is also capable of binding to gp130 and inducing intracellular signaling. Through this so-called 'trans-signaling' mechanism, IL-6 can stimulate cells that lack an endogenous mIL-6R. High levels of IL-6 and SIL-6R have been reported in several chronic inflammatory and autoimmune diseases as well as in cancer.Cancer ImmunotherapyImmune CheckpointImmunotherapyTargeted Therapy |
| Conjucates | PE |
| Others Formats | Unconjugated/APC/FITC |
| Antibody Types Available | 4 |
| Immunogen | Recombinant Protein: Human IL6R / CD126 Protein (TMPY-00864) |
| Antigen Species | Human |
| Biology Area | Neuroinflammation |
| Stability & Storage | Store at 2°C-8°C for 12 months, do not freeze. Keep away from direct sunlight. |
| Transport | Shipping with blue ice. |
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