Powder: -20°C for 3 years | In solvent: -80°C for 1 year
FSCPX is a potent and selective irreversible antagonist of the A1 adenosine receptor (A1AR), exhibiting low nanomolar binding potency. Additionally, FSCPX can effectively decrease the interstitial adenosine level in the guinea pig atrium, thereby modifying the effect of NBTI, a nucleoside transport inhibitor.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 228.00 | |
5 mg | In stock | $ 579.00 | |
10 mg | In stock | $ 829.00 | |
25 mg | In stock | $ 1,260.00 | |
50 mg | In stock | $ 1,680.00 | |
100 mg | In stock | $ 2,280.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 196.00 |
Description | FSCPX is a potent and selective irreversible antagonist of the A1 adenosine receptor (A1AR), exhibiting low nanomolar binding potency. Additionally, FSCPX can effectively decrease the interstitial adenosine level in the guinea pig atrium, thereby modifying the effect of NBTI, a nucleoside transport inhibitor. |
Targets&IC50 | DDT1 MF2 cells:11.8±3.2 nM |
In vitro |
FSCPX (2-20 μM ; 48 h) reverses the upregulation of HSP27 mRNA and protein in A1AR-overexpressing LLC-PK1 cells without an effect on the mRNA or protein for HSP70.[3] FSCPX (20 μM ; 48 h) attenuates protection from necrosis and apoptosis in A1AR-overexpressing LLC-PK1 cells.[3] |
Molecular Weight | 506.55 |
Formula | C23H27FN4O6S |
CAS No. | 156547-56-7 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 45.0 mg/mL (88.8 mM ), Sonication and heating to 60℃ are recommended.
You can also refer to dose conversion for different animals. More
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FSCPX 156547-56-7 GPCR/G Protein Neuroscience Adenosine Receptor inhibitor inhibit