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Vopikitug

(Synonyms: RO7296682, RO 7296682, RG6292, RG 6292) Copy Product Info
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Synonyms: RO7296682, RO 7296682, RG6292, RG 6292

Catalog No. T80854 Copy Product Info
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Vopikitug is a humanized monoclonal antibody targeting IL-2RA with antitumor activity. It can be used to study cancer.
Vopikitug
Cas No. 2733581-99-0
Pack SizePriceUSA StockGlobal StockQuantity
1 mg$149-In Stock
5 mg$368-In Stock
10 mg$547-In Stock
25 mg$883-In Stock
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Batch Information

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Purity:99.1% (SDS-PAGE); 96.5% (SEC-HPLC)
Appearance:Liquid
Color:Transparent
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Product Introduction

Bioactivity
Description
Vopikitug is a humanized monoclonal antibody targeting IL-2RA with antitumor activity. It can be used to study cancer.
In vitro
Vopikitug exerts its antitumor activity by targeting CD25 (IL-2Rα), a marker that is highly expressed on the surface of regulatory T cells (TREGs). By specifically binding to CD25, Vopikitug was able to selectively consume TreGs, potentially enhancing the body's immune response to tumors. [1]
SynonymsRO7296682, RO 7296682, RG6292, RG 6292
Reactivity
Human
Verified Activity
Immobilized Human CD25/IL2R Protein (His) (TMPY-01103) at 1 μg/mL (100 μL/well) can bind Vopikitug. The EC50 is 3.76 ng/mL.
Vopikitug
Application
Functional assay
Antibody Type
Monoclonal
FormulationSupplied as a sterile solution in a buffered formulation system (e.g., phosphate-, citrate-, or amino acid-based). Please refer to the CoA for lot-specific composition.
Endotoxin<1.0 EU/mg
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
TargetIL-2RA
Chemical Properties
Molecular Weight144.53 kDa
Cas No.2733581-99-0
Antibody Information
IsotypeHuman IgG1 kappa
Recommended Isotype Control
Storage & Solubility Information
StorageStore at low temperature -20°C for 1 year Shipping with blue ice/Shipping at ambient temperature.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
Related Tags: Vopikitug chemical structure | Vopikitug in vitro | Vopikitug molecular weight